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Western blot - AMPD1 antibody (ab72541)
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - AMPD1 antibody (ab72541)
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Product Name
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AMPD1 antibody
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See all AMPD1 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to AMPD1
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Immunogen
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Synthetic peptide corresponding to a region between residues 140 and 190 of human AMPD1 (NP_000027).
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Reacts with
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Hu, Ms, Rat, Cow, Dog, Mk
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Predicted to react
(species key)
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Chmp
(Due to sequence homology)
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Tested applications
(see key)
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IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: Use at a concentration of 10 µg/ml.
WB: Use at a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 87 kDa (predicted molecular weight: 87 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Mouse and rat skeletal muscle lysates. Human skeletal muscle tissue.
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Research areas
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Signal Transduction >> Metabolism >> Energy Metabolism
Chromatin and Nuclear Signaling >> DNA / RNA >> DNA / Nucleotides
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Relevance
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AMP deaminase (AMPD) is an allosteric enzyme that plays a critical role in energy metabolism. There are three functional isoforms of AMPD. AMPD1 is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. Defects in AMPD1 are the cause of adenosine monophosphate deaminase deficiency muscle type (AMPDDM). AMPDDM is a metabolic disorder resulting in exercise-related myopathy. It is characterized by exercise-induced muscle aches, cramps, and early fatigue.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.05% Sodium Azide
Constituents: 0.2% Gelatin, PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this AMPD1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for AMPD1 antibody images, references, products related to ab72541 and other tools.
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AMPD1 antibody images:
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 Western blot - AMPD1 antibody (ab72541)
All lanes : AMPD1 antibody (ab72541) at 1 µg/ml
Lane 1 : Mouse skeletal muscle lysate
Lane 2 : Mouse skeletal muscle lysate with immunising peptide
Lane 3 : Rat skeletal muscle lysate
Predicted band size : 87 kDa
Observed band size : 87 kDa
Additional bands at : 10 kDa. We are unsure as to the identity of these extra bands.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - AMPD1 antibody (ab72541)
ab72541 at 10µg/ml staining AMPD1 in human skeletal muscle by Immunohistochemistry using paraffin-embedded tissue.
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Search PubMed (MEDLINE) for references to AMPD1
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AMPD1 antibody - more information
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Customer reviews (feedback) regarding AMPD1 antibody |
Customer FAQs regarding AMPD1 antibody |
Protocols for AMPD1 antibody |
Price and availability of products related to AMPD1 antibody |
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AMPD1 antibody - related products:
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AMPD1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about AMPD1 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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