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Product Name
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ANP antibody [L11-11-D6-B4]
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See all ANP antibodies (12)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [L11-11-D6-B4] to ANP
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Immunogen
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Poly Lysin conjugated synthetic peptide: SLRRSSCFGGRMDRFGAQSGLGCNSFRY, corresponding to amino acids 1-28 of Human ANP.
BLAST 'SLRRSSCFGGRMDRFGAQSGLGCNSFRY' with  or 
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Reacts with
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Hu
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Predicted to react
(species key)
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Ms, Rat, Cat, Cow, Dog, Gpig, Hrs, Pig, Rb, Shp
(Due to sequence homology)
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Specificity
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ab14442 recognizes synthetic ANP.
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Tested applications
(see key)
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ELISA
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Cardiovascular >> Heart >> Hypertrophy >> Other
Cardiovascular >> Heart >> Hypertrophy >> Hormones
Cardiovascular >> Blood >> Blood Pressure regulation
Signal Transduction >> Growth Factors/Hormones >> Hormones
Cardiovascular >> Blood >> Other
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Relevance
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Atrial natriuretic factor (ANP) is a potent vasoactive substance which is thought to play a key role in cardiovascular homeostasis and has a cGMP stimulating activity. There are two different prepronatriodilatin alleles. One codes for 2 Arginine residues at the C terminus that are cleaved to form the mature peptide, while the other ends in a termination codon immediately after the last codon of the mature peptide. ANP belongs to the natriuretic peptide family.
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ANP antibody [L11-11-D6-B4] (ab14442) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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L11-11-D6-B4
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Isotype
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IgG1
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
Constituents: 50mM Tris HCl. pH 7.4
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Purification notes
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Cell culture supernatant, Protein G purified.
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ANP antibody [L11-11-D6-B4] is on this datasheet. But please do contact us if you would like any reassurance! |
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References for ANP antibody [L11-11-D6-B4] (ab14442)
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This product has been used in:
Bovill E et al. Induction by left ventricular overload and left ventricular failure of the human Jumonji gene (JARID2) encoding a protein that regulates transcription and reexpression of a protective fetal program. J Thorac Cardiovasc Surg 136:709-16 (2008). PubMed: 18805276
If you publish research using ab14442 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to ANP
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ANP antibody [L11-11-D6-B4] - more information
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Customer reviews (feedback) regarding ANP antibody [L11-11-D6-B4] |
Customer FAQs regarding ANP antibody [L11-11-D6-B4] |
Protocols for ANP antibody [L11-11-D6-B4] |
Price and availability of products related to ANP antibody [L11-11-D6-B4] |
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ANP antibody [L11-11-D6-B4] - related products:
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ANP antibody [L11-11-D6-B4] - other tools:
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Contact Abcam with a Technical Enquiry about ANP antibody [L11-11-D6-B4] |
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