Overview

  • Product nameAnti-ANP antibody
    See all ANP primary antibodies
  • Description
    Sheep polyclonal to ANP
  • Tested applicationsELISA, RIAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Poly Lysin conjugated synthetic peptide:

    SLRRSSCFGGRMDRFGAQSGLGCNSFRY

    , corresponding to amino acids 1-28 of Human ANP.

Properties

Applications

Our Abpromise guarantee covers the use of ab14354 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
RIA Use at an assay dependent dilution.

Target

  • FunctionHormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilatation. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • Involvement in diseaseDefects in NPPA are the cause of atrial fibrillation familial type 6 (ATFB6) [MIM:612201]. Atrial fibrillation is a common disorder of cardiac rhythm that is hereditary in a small subgroup of patients. It is characterized by disorganized atrial electrical activity, progressive deterioration of atrial electromechanical function and ineffective pumping of blood into the ventricles. It can be associated with palpitations, syncope, thromboembolic stroke, and congestive heart failure.
  • Sequence similaritiesBelongs to the natriuretic peptide family.
  • Post-translational
    modifications
    Cleaved by CORIN upon secretion to produce the functional hormone.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • ANF antibody
    • ANF_HUMAN antibody
    • ANP antibody
    • ATFB6 antibody
    • Atrial natriuretic factor antibody
    • Atrial natriuretic factor precursor antibody
    • Atrial natriuretic peptide antibody
    • Atriopeptin antibody
    • Cardionatrin antibody
    • CDD ANF antibody
    • CDD-ANF antibody
    • CDP antibody
    • Natriuretic peptide A antibody
    • Natriuretic Peptide Precursor A antibody
    • NPPA antibody
    • PND antibody
    • Prepronatriodilatin antibody
    see all

References for Anti-ANP antibody (ab14354)

ab14354 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"