Anti-ANP antibody (ab14354)
- Product nameAnti-ANP antibodySee all ANP primary antibodies ...
- DescriptionSheep polyclonal to ANP
- Tested applicationsELISA, RIA more details
- Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Sheep, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
Poly Lysin conjugated synthetic peptide: SLRRSSCFGGRMDRFGAQSGLGCNSFRY, corresponding to amino acids 1-28 of Human ANP.
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
Constituents: Whole Serum
- PurityWhole antiserum
- Clonality Polyclonal
- Research Areas
Our Abpromise guarantee covers the use of ab14354 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||ELISA: Use at an assay dependent dilution.|
|RIA||RIA: Use at an assay dependent dilution.|
- FunctionHormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilatation. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
- Involvement in diseaseDefects in NPPA are the cause of atrial fibrillation familial type 6 (ATFB6) [MIM:612201]. Atrial fibrillation is a common disorder of cardiac rhythm that is hereditary in a small subgroup of patients. It is characterized by disorganized atrial electrical activity, progressive deterioration of atrial electromechanical function and ineffective pumping of blood into the ventricles. It can be associated with palpitations, syncope, thromboembolic stroke, and congestive heart failure.
- Sequence similaritiesBelongs to the natriuretic peptide family.
modificationsCleaved by CORIN upon secretion to produce the functional hormone.
- Cellular localizationSecreted.
- Entrez Gene: 281355 Cow
- Entrez Gene: 608289 Dog
- Entrez Gene: 4878 Human
- Entrez Gene: 230899 Mouse
- Entrez Gene: 24602 Rat
- Omim: 108780 Human
- SwissProt: Q9GLD0 Cat
- SwissProt: P07501 Cow
- SwissProt: P07499 Dog
- SwissProt: P27104 Horse
- SwissProt: P01160 Human
- SwissProt: P05125 Mouse
- SwissProt: P07500 Rabbit
- SwissProt: P01161 Rat
- SwissProt: O46540 Sheep
- Unigene: 75640 Human
- ANF antibody
- ANF_HUMAN antibody
- ANP antibody
- ATFB6 antibody
- Atrial natriuretic factor antibody
- Atrial natriuretic factor precursor antibody
- Atrial natriuretic peptide antibody
- Atriopeptin antibody
- Cardionatrin antibody
- CDD ANF antibody
- CDD-ANF antibody
- CDP antibody
- Natriuretic peptide A antibody
- Natriuretic Peptide Precursor A antibody
- NPPA antibody
- PND antibody
- Prepronatriodilatin antibody
References for Anti-ANP antibody (ab14354)
ab14354 has not yet been referenced specifically in any publications.