Overview

  • Product nameAnti-AP1M2 antibodySee all AP1M2 primary antibodies ...
  • Description
    Mouse polyclonal to AP1M2
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    AP1M2 (NP_005489, 423 a.a), full-length human protein.

  • Positive control
    • AP1M2 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab70143 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa).

Target

  • FunctionSubunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
  • Sequence similaritiesBelongs to the adaptor complexes medium subunit family.
    Contains 1 MHD (mu homology) domain.
  • Post-translational
    modifications
    Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals.
  • Cellular localizationGolgi apparatus. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adaptor protein complex AP-1 mu-2 subunit antibody
    • Adaptor protein complex AP1 mu2 subunit antibody
    • Adaptor related protein complex 1 mu2 subunit antibody
    • Adaptor-related protein complex 1 mu-2 subunit antibody
    • AP mu chain family member mu1B antibody
    • AP-1 complex subunit mu-2 antibody
    • AP-mu chain family member mu1B antibody
    • AP1 complex subunit mu2 antibody
    • AP1M2 antibody
    • AP1M2_HUMAN antibody
    • AP47 2 antibody
    • Clathrin assembly protein complex 1 medium chain 2 antibody
    • Golgi adaptor HA1/AP1 adaptin mu-2 subunit antibody
    • Golgi adaptor HA1/AP1 adaptin mu2 subunit antibody
    • HA1 47 kDa subunit 2 antibody
    • HSMU1B antibody
    • MU 1B antibody
    • Mu adaptin 2 antibody
    • Mu-adaptin 2 antibody
    • Mu1B adaptin antibody
    • Mu1B-adaptin antibody
    see all

Anti-AP1M2 antibody images

  • All lanes : Anti-AP1M2 antibody (ab70143) at 1/500 dilution

    Lane 1 : AP1M2 transfected 293T cell lysate
    Lane 2 : non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 48 kDa
    Observed band size : 48 kDa

References for Anti-AP1M2 antibody (ab70143)

ab70143 has not yet been referenced specifically in any publications.

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