Anti-AP1M2 antibody (ab70143)

Overview

• Product nameAnti-AP1M2 antibodySee all AP1M2 primary antibodies ...
• Description
  Mouse polyclonal to AP1M2
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  AP1M2 (NP_005489, 423 a.a), full-length human protein.

• Positive controlAP1M2 transfected 293T cell lysate

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: 1X PBS, pH 7.2
• Concentration information loading...
• PurityProtein G purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Signal Transduction
  • Protein Trafficking
  • Vesicle Transport
  • Adapters

  • Signal Transduction
  • Adapters
  • Cytoplasmic

Applications

Target

• FunctionSubunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
• Sequence similaritiesBelongs to the adaptor complexes medium subunit family.
  Contains 1 MHD (mu homology) domain.
• Post-translational
  modificationsPhosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals.
• Cellular localizationGolgi apparatus. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.

Target information above from: UniProt accession Q9Y6Q5 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 10053 Human
  • Omim: 607309 Human
  • SwissProt: Q9Y6Q5 Human
  • Unigene: 18894 Human

• Alternative names
  Adaptor protein complex AP-1 mu-2 subunit antibodyAdaptor protein complex AP1 mu2 subunit antibodyAdaptor related protein complex 1 mu2 subunit antibody

  Adaptor-related protein complex 1 mu-2 subunit antibodyAP mu chain family member mu1B antibodyAP-1 complex subunit mu-2 antibodyAP-mu chain family member mu1B antibodyAP1 complex subunit mu2 antibodyAP1M2 antibodyAP1M2_HUMAN antibodyAP47 2 antibodyClathrin assembly protein complex 1 medium chain 2 antibodyGolgi adaptor HA1/AP1 adaptin mu-2 subunit antibodyGolgi adaptor HA1/AP1 adaptin mu2 subunit antibodyHA1 47 kDa subunit 2 antibodyHSMU1B antibodyMU 1B antibodyMu adaptin 2 antibodyMu-adaptin 2 antibodyMu1B adaptin antibodyMu1B-adaptin antibody

  see all

Anti-AP1M2 antibody images

• 

  Western blot - AP1M2 antibody (ab70143)
  All lanes : Anti-AP1M2 antibody (ab70143) at 1/500 dilution
  
  Lane 1 : AP1M2 transfected 293T cell lysate
  Lane 2 : non transfected 293T cell lysate
  
  Lysates/proteins at 25 µg per lane.
  
  Secondary
  Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
  
  Predicted band size : 48 kDa
  Observed band size : 48 kDa