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Western blot - AP2M1 antibody (ab13992)
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Product Name
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AP2M1 antibody
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See all AP2M1 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Chicken polyclonal to AP2M1
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Immunogen
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Recombinant full length protein, corresponding to amino acids 1-435 of Human AP2M1.
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Reacts with
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Hu, Ms, Dog
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Tested applications
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WB
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Abreviews
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Application notes
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Recommended dilutions
WB: 1/500 - 1/2000. Predicted molecular weight: 48 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Plasma membrane
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Research areas
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Signal Transduction >> Protein Trafficking >> Vesicle Transport >> Coat Proteins
Signal Transduction >> Protein Trafficking >> Vesicle Transport >> Adapters
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Relevance
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AP2M1 is a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. It is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. It may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Chicken
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Clonality
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Polyclonal
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Isotype
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IgY
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: None
Constituents: PBS
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Purification notes
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Peptide immunogen affinity column.
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this AP2M1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for AP2M1 antibody images, references, products related to ab13992 and other tools.
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AP2M1 antibody images:
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 Western blot - AP2M1 antibody (ab13992)
Predicted band size : 48 kDa
ab13992 at 1/1000 dilution staining E coli-derived fusion protein as test antigen by Western blot (Colorimetric method ).
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References for AP2M1 antibody (ab13992)
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This product has been used in: (two most recent references)
Diaz F et al. Clathrin adaptor AP1B controls adenovirus infectivity of epithelial cells. Proc Natl Acad Sci U S A 106:11143-8 (2009). WB; Dog. PubMed: 19549835
Deborde S et al. Clathrin is a key regulator of basolateral polarity. Nature 452:719-23 (2008). WB; Dog. PubMed: 18401403
See all 3 publication references for this product.
If you publish research using ab13992 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to AP2M1
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AP2M1 antibody - more information
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Customer reviews (feedback) regarding AP2M1 antibody |
Customer FAQs regarding AP2M1 antibody |
Protocols for AP2M1 antibody |
Price and availability of products related to AP2M1 antibody |
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AP2M1 antibody - related products:
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AP2M1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about AP2M1 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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