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Overview

  • Product nameAnti-APC2 antibodySee all APC2 primary antibodies ...
  • Description
    Rabbit polyclonal to APC2
  • Tested applicationsWB, ELISA, IHC-P, ICC more details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids of Human APC2 (NP_005874.1).

  • Positive controlHuman Brain Cortex and Small Intestine tissues; HeLa cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab113370 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 244 kDa.
ELISA ELISA: Use at an assay dependent dilution.
IHC-P IHC-P: Use a concentration of 5 µg/ml.
ICC ICC: Use at an assay dependent dilution.

Target

  • RelevanceAPC2 might function in the Wnt signaling pathway through it's ability to promote the rapid degradation of beta-catenin. It also functions as a tumour suppressor.
  • Cellular localizationCell Membrane, Cytoplasmic and Golgi Apparatus
  • Database links
    • Alternative names
        Adenomatous polyposis coli protein 2 antibodyAdenomatous polyposis coli protein-like antibodyAPCL antibody

    Anti-APC2 antibody images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APC2 antibody (ab113370)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APC2 antibody (ab113370)
      ab113370, at 5 µg/ml, staining APC2 in Formalin-fixed, Paraffin-embedded Human Brain cortex tissue by Immunohistochemistry.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APC2 antibody (ab113370)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APC2 antibody (ab113370)
      ab113370, at 5 µg/ml, staining APC2 in Formalin-fixed, Paraffin-embedded Human Small intestine tissue by Immunohistochemistry.
    • Western blot - Anti-APC2 antibody (ab113370)
      Western blot - Anti-APC2 antibody (ab113370)
      Lane 1 : Anti-APC2 antibody (ab113370) at 1 µg/ml
      Lane 2 : Anti-APC2 antibody (ab113370) at 2 µg/ml

      Lane 1 : HeLa cell lysate
      Lane 2 : HeLa cell lysate


      Predicted band size : 244 kDa

    References for Anti-APC2 antibody (ab113370)

    This product has been referenced in:
    • Hebert AM  et al. Merlin/ERM proteins establish cortical asymmetry and centrosome position. Genes Dev 26:2709-23 (2012). WB ; Human . Read more (PubMed: 23249734) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"