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Western blot - APE1 antibody (ab13902)
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Product Name
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APE1 antibody
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See all APE1 antibodies (16)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to APE1
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Immunogen
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KLH conjugated synthetic peptides corresponding to amino acids 36-52 and 216-232 of human APE.
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1 - 2 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 35 kDa).
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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HeLa cell lysates.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Base Excision Repair
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Relevance
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Apurinic / apyrimidinic endonuclease (APE1 or REF1) is responsible for the incision of DNA basic sites during base excision repair. It has also been shown to stimulate the DNA binding activity of numerous transcription factors that are involved in cancer promotion and progression. Alterations in APE1 levels have been described in some cancers. APE1 is part of the cellular response to oxidative stress and protects cells from the genotoxic and cytotoxic effect of oxidizing agents.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this APE1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for APE1 antibody images, references, products related to ab13902 and other tools.
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APE1 antibody images:
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 Western blot - APE1 antibody (ab13902)
Predicted band size : 35 kDa
Western blot analysis of APE in HeLa cell lysates using ab13902 at a dilution of 2 ug/ml.
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Search PubMed (MEDLINE) for references to APE1
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APE1 antibody - more information
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Customer reviews (feedback) regarding APE1 antibody |
Customer FAQs regarding APE1 antibody |
Protocols for APE1 antibody |
Price and availability of products related to APE1 antibody |
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APE1 antibody - related products:
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APE1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about APE1 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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