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Anti-APLP2 antibody (ab54432)

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Overview

Product name

Anti-APLP2 antibody
See all APLP2 products (3) ...

Description

Rabbit polyclonal to APLP2

Specificity

Does not react with APP and APLP1.

Tested applications

WB, IP, ICC/IFmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Predicted to work with

Xenopus laevis

Immunogen

Synthetic peptide: NPTYKYLEQMQI conjugated to KLH by a Cysteine residue linker, corresponding to amino acids 752-763 of Mouse APLP2

NPTYKYLEQM QI

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: Whole serum

Purity

Whole antiserum

Clonality

Polyclonal

Isotype

IgG

Research areas

Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Amyloid

Applications

Show applications key

Our Abpromise guarantee covers the use of ab54432 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide

    WB

     WB: 1/1000 - 1/5000.Pred...Read more →

    WB: 1/1000 - 1/5000.Predicted molecular weight: 87 kDa.

  • ShowHide

    IP

     IP: Use at an assay depe...Read more →

    IP: Use at an assay dependent dilution. (Use 1-2 µl/mg cell or tissue lysate )

  • ICC/IF

     ICC/IF: 1/250 - 1/500.

    ICC/IF: 1/250 - 1/500.

Target

Function

May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.

Tissue specificity

Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.

Sequence similarities

Belongs to the APP family.
Contains 1 BPTI/Kunitz inhibitor domain.

Post-translational
modifications

The BPTI/Kunitz inhibitor domain is O-glycosylated.

Cellular localization

Cell membrane. Nucleus.

Target information above from: UniProt accessionQ06481 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • amyloid beta (A4) precursor like protein 2 antibody
  • Amyloid like protein 2 antibody
  • amyloid precursor protein homolog HSD2 antibody
  • Amyloid protein homolog antibody
  • Amyloid-like protein 2 antibody
  • APLP-2 antibody
  • Aplp2 antibody
  • APLP2_HUMAN antibody
  • APPH antibody
  • APPL2 antibody
  • CDEBP antibody
  • CDEI box binding protein antibody
  • CDEI box-binding protein antibody
see all

Database links

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References for Anti-APLP2 antibody (ab54432)

ab54432 has not yet been referenced specifically in any publications.

Publishing research using ab54432? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"