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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - APLP2 antibody (ab58583)
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Product Name
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APLP2 antibody
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See all APLP2 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to APLP2
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Immunogen
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Full length APLP2 protein (Mouse)
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Reacts with
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Hu, Ms, Rat
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Specificity
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Does not cross-react with APP and APLP1.
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Tested applications
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ICC/IF, IHC-Fr, IHC-P, IP, WB
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Abreviews
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Application notes
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Recommended dilutions
ICC/IF: 1/250 - 1/500.
IHC-Fr: 1/1000.
IHC-P: 1/1000.
IP: Use at 1-2µg/mg of lysate.
WB: 1/5000 - 1/20000. Predicted molecular weight: 87 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cell Membrane; single pass type I membrane protein and Nuclear
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Research areas
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Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Amyloid
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Relevance
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APLP2 may play a role in the regulation of hemostasis. It may interact with cellular G-protein signaling pathways.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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Preservative: None
Constituents: Whole serum
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this APLP2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for APLP2 antibody images, references, products related to ab58583 and other tools.
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APLP2 antibody images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - APLP2 antibody (ab58583)
Immunohistochemistical detection of APLP2 using antibody ab58583 on (Formaldehyde-fixed paraffin-embedded rat lumbar DRG sections). Antigen retrieval step: heat mediated; Buffer used: Citric acid pH6; Blocking step: 1% BSA for 10 mins@ rt°C. Primary antibody ab58583 diluted @ 1/1000, incubated for 16 hours in TBS/BSA/azide. Secondary antibody: anti Rabbit IgG conjugated to biotin (1/200). The immunostaining appears to be localised to the cytoplasm: a widely distributed punctate positivity is seen in DRG cells. Note that DRG nuclei are "absent": Citric acid HIER pH6, in my hands, tends to hydrolyse DNA in highly metabolically active cells. NB: other nuclei are very well stained. I overstained this section with Hx: note the blue staining of the myelin sheaths. Carl Hobbs, King`s College London, United Kingdom
See Abreview
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Search PubMed (MEDLINE) for references to APLP2
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APLP2 antibody - more information
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Customer reviews (feedback) regarding APLP2 antibody |
Customer FAQs regarding APLP2 antibody |
Protocols for APLP2 antibody |
Price and availability of products related to APLP2 antibody |
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APLP2 antibody - related products:
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APLP2 antibody - other tools:
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Contact Abcam with a Technical Enquiry about APLP2 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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