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Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
Overview
Product name
Anti-APOBEC1 antibody
See all APOBEC1 products (2) ...
Description
Rabbit polyclonal to APOBEC1
Tested applications
WB, IHC-P, ELISAmore details
Cross reactivity
Reacts with
Mouse, Human
Immunogen
A KLH conjugated synthetic peptide designed within the first 50 aa of human APOBEC1 (N-terminal).
Positive control
Mouse small intestine tissue lysate and human hepatocarcinoma tissue.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Purification notes
This antibody is purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS.
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
Applications
Show applications key
Our Abpromise guarantee covers the use of ab38601 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/100 - 1/500.Detects a band of approximately 31 kDa (predicted molecular weight: 28 kDa).
IHC-P: 1/50 - 1/100.
ELISA
ELISA: 1/1000ELISA: 1/1000
Target
Function
Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA.
Tissue specificity
Expressed exclusively in the small intestine.
Sequence similarities
Belongs to the cytidine and deoxycytidylate deaminase family.
Target information above from: UniProt accessionP41238
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- ABEC1_HUMAN antibody
- APOBEC 1 antibody
- APOBEC1 antibody
see all
Database links
- Entrez Gene: 339 Human
- Entrez Gene: 11810 Mouse
- GenBank: L25877 Human
- GenBank: U21951 Mouse
- Omim: 600130 Human
- SwissProt: P41238 Human
- SwissProt: P51908 Mouse
- SwissProt: Q3TLN2 Mouse
see all
Anti-APOBEC1 antibody images:
Western blot - APOBEC1 antibody (ab38601)
Anti-APOBEC1 antibody (ab38601) at 1/100 dilution + mouse small intestine tissue lysate
Predicted band size : 28 kDa
Observed band size : 31 kDa (why is the actual band size different from the predicted?)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - APOBEC1 antibody (ab38601)
Staining of APOBEC1 on formalin-fixed and paraffin-embedded human hepatocarcinoma tissue with ab38601, detected using a peroxidase-conjugated secondary antibody, followed by AEC staining.
References for Anti-APOBEC1 antibody (ab38601)
ab38601 has not yet been referenced specifically in any publications.
Publishing research using ab38601? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"