Anti-ARA9 antibody (ab115588)

Overview

• Product nameAnti-ARA9 antibodySee all ARA9 primary antibodies ...
• Description
  Goat polyclonal to ARA9
• Tested applicationsWB, ELISA, IHC-P more details
• Species reactivity
  Reacts with: Mouse, Human
  Predicted to work with: Rat, Cow, Dog
• Immunogen

  Synthetic peptide: EARIRQKDEEDKAR with a Cysteine residue linker, corresponding to C terminal amino acids 310-323 of Human ARA9 (NP_003968.2).

  Run BLAST with Run BLAST with
• Positive controlNIH3T3 cell lysate; Human Placenta tissue.

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
• Storage bufferpH: 7.30
  Preservative: 0.02% Sodium azide
  Constituents: 99% Tris buffered saline, 0.5% BSA
• Concentration information loading...
• PurityProtein G purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Neuroscience
  • Neurotransmission
  • Receptors / Channels
  • More Ion Channels

Applications

Target

• FunctionMay play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.
  Cellular negative regulator of the hepatitis B virus (HBV) X protein.
• Tissue specificityWidely expressed. Higher levels seen in the heart, placenta and skeletal muscle. Not expressed in the liver.
• Involvement in diseaseDefects in AIP are a cause of familial isolated pituitary adenoma (FIPA) [MIM:102200].
  Defects in AIP are a cause of growth hormone-secreting pituitary adenoma (GHSPA) [MIM:102200]; also known as familial isolated somatotropinomas (FIS) or isolated familial somatotropinoma (IFS) or familial somatotrophinoma or acromegaly due to pituitary adenoma.
  Defects in AIP are a cause of ACTH-secreting pituitary adenoma (ASPA) [MIM:219090]; also known as pituitary Cushing disease. A pituary adenoma resulting in excessive production of adrenocorticotropic hormone. This leads to hypersecretion of cortisol by the adrenal glands and ACTH-dependent Cushing syndrome. Clinical manifestations of Cushing syndrome include facial and trunkal obesity, abdominal striae, muscular weakness, osteoporosis, arterial hypertension, diabetes.
  Defects in AIP are a cause of prolactin-secreting pituitary adenoma (PSPA) [MIM:600634]; also known as prolactinoma. Prolactin-secreting pituitary adenoma is the most common type of hormonally active pituitary adenoma.
• Sequence similaritiesContains 1 PPIase FKBP-type domain.
  Contains 2 TPR repeats.
• Cellular localizationCytoplasm.

Target information above from: UniProt accession O00170 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 360190 Cow
  • Entrez Gene: 610467 Dog
  • Entrez Gene: 9049 Human
  • Entrez Gene: 11632 Mouse
  • Entrez Gene: 282827 Rat
  • Omim: 605555 Human
  • SwissProt: Q7YRC1 Cow
  • SwissProt: O00170 Human

  • SwissProt: O08915 Mouse
  • SwissProt: Q5FWY5 Rat
  • Unigene: 20864 Dog
  • Unigene: 412433 Human
  • Unigene: 10433 Mouse
  • Unigene: 95160 Rat

  see all

• Alternative names
  AH receptor interacting protein antibodyAH receptor-interacting protein antibodyAIP antibody

  AIP antibodyAIP_HUMAN antibodyARA 9 antibodyAryl hydrocarbon receptor interacting protein antibodyAryl-hydrocarbon receptor-interacting protein antibodyfa03h10 antibodyFKBP 16 antibodyFKBP 37 antibodyFKBP16 antibodyFKBP37 antibodyHBV X associated protein 2 antibodyHBV X associated protein antibodyHBV X-associated protein 2 antibodyHBVX associated protein antibodyImmunophilin homolog ARA 9 antibodyImmunophilin homolog ARA9 antibodySMTPHN antibodyXAP 2 antibodyXAP-2 antibodyXAP2 antibody

  see all

Anti-ARA9 antibody images

• 

  Western blot - Anti-ARA9 antibody (ab115588)
  Anti-ARA9 antibody (ab115588) at 0.02 µg/ml + NIH3T3 cell lysate (in RIPA buffer) at 35 µg
  developed using the ECL technique
  
  Predicted band size : 37 kDa
  
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ARA9 antibody (ab115588)
  ab115588, at 5 µg/ml, staining ARA9 in Formalin-fixed, Paraffin-embedded Human Placenta tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.