AREB6 peptide (ab66485)
- AREB 6BZPDelta crystallin enhancer binding factor 1
- DELTA EF1FECD6MGC133261Negative regulator of IL 2Negative regulator of IL2NIL 2 ANIL 2 A zinc finger proteinNIL 2ANIL-2-A zinc finger proteinNIL2APosterior polymorphous corneal dystrophy 3PPCD3Represses interleukin 2 expressionTCF 8TCF-8TCF8Transcription factor 8Transcription factor 8 (represses interleukin 2 expression)ZEBZEB 1ZEB1ZEB1_HUMANZFHEPZFHX 1AZFHX1AZinc finger E box binding homeobox 1Zinc finger E-box-binding homeobox 1Zinc finger homeodomain enhancer binding protein
Defects in ZEB1 are the cause of corneal dystrophy Fuchs endothelial type 6 (FECD6) [MIM:613270]. It is an ocular disorder caused by loss of endothelium of the central cornea. It is characterized by focal wart-like guttata that arise from Descemet membrane and develop in the central cornea, epithelial blisters, reduced vision and pain. Descemet membrane is thickened by abnormal collagenous deposition.
Contains 7 C2H2-type zinc fingers.
Contains 1 homeobox DNA-binding domain.
References for AREB6 peptide (ab66485)
ab66485 has not yet been referenced specifically in any publications.