Anti-ARHGEF10 antibody (ab168936)
Key features and details
- Mouse polyclonal to ARHGEF10
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ARHGEF10 antibody -
Description
Mouse polyclonal to ARHGEF10 -
Host species
Mouse -
Tested applications
Suitable for: WB, ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to amino acids 207-570 of Human ARHGEF10 Isoform 3 (AAH40474.1)
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Positive control
- ARHGEF10-transfected 293T cell lysate. HeLa cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.4
Constituent: 99% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab168936 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 152 kDa.
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ICC/IF |
Use a concentration of 10 µg/ml.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 152 kDa. |
ICC/IF
Use a concentration of 10 µg/ml. |
Target
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Function
May play a role in developmental myelination of peripheral nerves. -
Involvement in disease
Defects in ARHGEF10 are the cause of slowed nerve conduction velocity (SNCV) [MIM:608236]. Affected individuals present a reduction in nerve conduction velocities without any clinical signs of peripheral or central nervous system dysfunction. SNCV inheritance is autosomal dominant. -
Sequence similarities
Contains 1 DH (DBL-homology) domain. - Information by UniProt
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Database links
- Entrez Gene: 9639 Human
- Omim: 608136 Human
- SwissProt: O15013 Human
- Unigene: 98594 Human
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Alternative names
- ARHGA_HUMAN antibody
- ARHGEF10 antibody
- DKFZp686H0726 antibody
see all
Images
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All lanes : Anti-ARHGEF10 antibody (ab168936) at 1 µg/ml
Lane 1 : ARHGEF10-transfected 293T cell lysate (41.8 KDa)
Lane 2 : non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Developed using the ECL technique.
Predicted band size: 152 kDa -
Immunofluorescent analysis of HeLa cells, labeling ARHGEF10 with ab168936 at 10 µg/ml.
Protocols
Datasheets and documents
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Datasheet download
References (0)
ab168936 has not yet been referenced specifically in any publications.