Overview

  • Product nameAnti-ARL2BP antibody [4C4]See all ARL2BP primary antibodies ...
  • Description
    Mouse monoclonal [4C4] to ARL2BP
  • Tested applicationsWB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length Human ARL2BP produced in E.coli (NP_036238).

  • Positive control
    • HEK293T cell lysate transfected with pCMV6-ENTRY ARL2BP cDNA; Human kidney carcinoma tissue.
  • General notesDilute in PBS (pH7.3) before use.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7,30
    Preservative: 0.02% Sodium azide
    Constituents: 48% PBS, 50% Glycerol, 1% BSA
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesab131633 was purified from mouse ascites fluids by affinity chromatography.
  • Clonality Monoclonal
  • Clone number4C4
  • IsotypeIgG1
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab131633 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 19 kDa.
IHC-P 1/150.

Target

  • FunctionTogether with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesBelongs to the ARL2BP family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm. Mitochondrion intermembrane space. Cytoplasm > cytoskeleton > centrosome. Nucleus. Cytoplasm > cytoskeleton > spindle. The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria (By similarity). Detected in the midbody matrix. Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules.
  • Information by UniProt
  • Database links
  • Alternative names
    • ADP ribosylation factor like 2 binding protein antibody
    • ADP-ribosylation factor-like protein 2-binding protein antibody
    • AR2BP_HUMAN antibody
    • Arf like 2 binding protein BART1 antibody
    • ARF-like 2-binding protein antibody
    • ARL2 binding protein antibody
    • Arl2bp antibody
    • ARL2BP protein antibody
    • BART antibody
    • BART1 antibody
    • Binder of ARF2 protein 1 antibody
    • Binder of Arl Two antibody
    • Binder of Arl2 antibody
    • Retinitis pigmentosa 66 (autosomal recessive) antibody
    • RP66 antibody
    see all

Anti-ARL2BP antibody [4C4] images

  • All lanes : Anti-ARL2BP antibody [4C4] (ab131633)

    Lane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control
    Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY ARL2BP cDNA

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 19 kDa
  • Immunohistochemical analysis of paraffin-embedded Human kidney carcinoma tissue labelling ARL2BP with ab131633 at 1/150 dilution.

References for Anti-ARL2BP antibody [4C4] (ab131633)

ab131633 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"