Anti-ARL2BP antibody [4C4] (ab131633)

Overview

• Product nameAnti-ARL2BP antibody [4C4]See all ARL2BP primary antibodies ...
• Description
  Mouse monoclonal [4C4] to ARL2BP
• Tested applicationsWB, IHC-P more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant full length Human ARL2BP produced in E.coli (NP_036238).

• Positive controlHEK293T cell lysate transfected with pCMV6-ENTRY ARL2BP cDNA; Human kidney carcinoma tissue.
• General notesDilute in PBS (pH7.3) before use.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Storage bufferpH: 7,30
  Preservative: 0.02% Sodium azide
  Constituents: 48% PBS, 50% Glycerol, 1% BSA
• Concentration information loading...
• PurityProtein G purified
• Purification notesab131633 was purified from mouse ascites fluids by affinity chromatography.
• Clonality Monoclonal
• Clone number4C4
• IsotypeIgG1
• Research Areas
  • Signal Transduction
  • Signaling Pathway
  • G Protein Signaling
  • Small G Proteins
  • Ras Family

Applications

Target

• FunctionTogether with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
• Tissue specificityUbiquitous.
• Sequence similaritiesBelongs to the ARL2BP family.
• Post-translational
  modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
• Cellular localizationCytoplasm. Mitochondrion intermembrane space. Cytoplasm > cytoskeleton > centrosome. Nucleus. Cytoplasm > cytoskeleton > spindle. The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria (By similarity). Detected in the midbody matrix. Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules.

Target information above from: UniProt accession Q9Y2Y0 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 23568 Human
  • SwissProt: Q9Y2Y0 Human
  • Unigene: 632873 Human

• Alternative names
  ADP ribosylation factor like 2 binding protein antibodyADP-ribosylation factor-like protein 2-binding protein antibodyAR2BP_HUMAN antibody

  Arf like 2 binding protein BART1 antibodyARF-like 2-binding protein antibodyArl2bp antibodyARL2BP protein antibodyBART antibodyBART1 antibodyBinder of ARF2 protein 1 antibodyBinder of Arl Two antibodyBinder of Arl2 antibody

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Anti-ARL2BP antibody [4C4] images

• 

  Western blot - Anti-ARL2BP antibody [4C4] (ab131633)
  All lanes : Anti-ARL2BP antibody [4C4] (ab131633)
  
  Lane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control
  Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY ARL2BP cDNA
  
  Lysates/proteins at 5 µg per lane.
  
  
  Predicted band size : 19 kDa
  
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ARL2BP antibody [4C4] (ab131633)
  Immunohistochemical analysis of paraffin-embedded Human kidney carcinoma tissue labelling ARL2BP with ab131633 at 1/150 dilution.