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Products:Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Small G Proteins >> Ras Family
Overview
Product name
ARL2BP protein (His tag)
See all ARL2BP products (2) ...
Protein description
Recombinant full length protein, corresponding to amino acids 1-163 of Human ARL2BP with a His-Tag at N-terminus.
Expression host
E. coli
Properties
Purity
>95% by SDS-PAGE
Form
Liquid
Storage instructions
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.002% Sodium Azide
Constituents: 3mM Sodium chloride, 2.5mM Imidazole, 10mM Tris, pH 8.
Concentration
Concentration information loading...
Research areas
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Small G Proteins >> Ras Family
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SDS-PAGE - ARL2BP protein (His tag) (ab40216)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab40216 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
SDS-PAGE: Use at an assay dependent dilution.
MS: Use at an assay dependent dilution.
Protein info
Relevance
ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this ARL2BP binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity.
Cellular localization
Cytoplasmic
ARL2BP protein (His tag) images:
SDS-PAGE - ARL2BP protein (His tag) (ab40216)
Analysis of ARL2BP Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining. The purified ARL2BP protein shows a band around 18kDa.
References for ARL2BP protein (His tag) (ab40216)
ab40216 has not yet been referenced specifically in any publications.
Publishing research using ab40216? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"