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Overview

  • Product nameAnti-ARMER antibodySee all ARMER primary antibodies ...
  • Description
    Rabbit polyclonal to ARMER
  • Tested applicationsICC/IF, WB, IHC-P more details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide, corresponding to 15 C terminal amino acids of Human ARMER (GenBank accession no. Q15041)

Properties

  • FormLiquid
  • Storage instructionsStore at +4°C.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purification notesIon exchange chromatography purified IgG
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab24228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
ICC/IF ICC/IF: Use a concentration of 20 µg/ml.
WB WB: Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 23 kDa).
IHC-P IHC-P: Use at an assay dependent dilution.

Target

  • FunctionMay be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.
  • Tissue specificityExpressed in all hematopoietic cell lineages, but the highest level of expression is found in early myeloid progenitor cells. Expressed in brain, bone marrow, thymus and lung. Expressed at low level in liver, kidney and spleen. Not detected in heart.
  • Sequence similaritiesBelongs to the ARL6ip family.
  • Developmental stageDown-regulated during myeloid differentiation.
  • Cellular localizationEndomembrane system. Predominantly localized to intracytoplasmic membranes.

    • Target information above from: UniProt accession Q15041 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        ADP ribosylation factor like 6 interacting protein antibodyADP-ribosylation factor-like protein 6-interacting protein 1 antibodyAip-1 antibody
        Aip1 antibodyAR6P1_HUMAN antibodyARL-6-interacting protein 1 antibodyARL6 interacting protein 1 antibodyARL6IP antibodyARL6IP1 antibodyKIAA0069 antibody
      see all

    Anti-ARMER antibody images

    • Western blot - ARMER antibody (ab24228)
      Western blot - ARMER antibody (ab24228)
      Lane 1 : Anti-ARMER antibody (ab24228) at 0.5 µg/ml
      Lane 2 : Anti-ARMER antibody (ab24228) at 1 µg/ml
      Lane 3 : Anti-ARMER antibody (ab24228) at 2 µg/ml

      Lane 1 : Human bladder cell lysate
      Lane 2 : Human bladder cell lysate
      Lane 3 : Human bladder cell lysate


      Predicted band size : 23 kDa
      Observed band size : 27 kDa (why is the actual band size different from the predicted?)
    • Immunohistochemistry (Paraffin-embedded sections) - ARMER antibody (ab24228)
      Immunohistochemistry (Paraffin-embedded sections) - ARMER antibody (ab24228)

      ab24228 at 2µg/ml staining of ARMER in human dladder tissue by IHC

    References for Anti-ARMER antibody (ab24228)

    ab24228 has not yet been referenced specifically in any publications.

    Publishing research using ab24228 ? Please let us know so that we can cite the reference in this datasheet

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