Overview
- Product nameAnti-ARMET antibodySee all ARMET primary antibodies ...
- DescriptionRabbit polyclonal to ARMET
- Tested applicationsWB, ICC/IF, IHC-P more details
- Species reactivityReacts with: Mouse, Rat, Human
- Immunogen
12 amino acid peptide from near the amino terminus of human MANF.
Properties
- FormLiquid
- Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: 0.02% Sodium Azide
Constituents: PBS -
Concentration information loading... - PurityPurified IgA
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab67203 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 20 kDa). |
| ICC/IF | ICC/IF: Use a concentration of 20 µg/ml. |
| IHC-P | IHC-P: Use a concentration of 2.5 µg/ml. |
Target
- FunctionSelectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
- Sequence similaritiesBelongs to the ARMET family.
- DomainThe N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.
- Post-translational
modificationsMay contain sialic acid residues. - Cellular localizationSecreted.
-
Database links
- Entrez Gene: 7873 Human
- Entrez Gene: 74840 Mouse
- Entrez Gene: 315989 Rat
- Omim: 601916 Human
- SwissProt: P55145 Human
- SwissProt: Q9CXI5 Mouse
- SwissProt: P0C5H9 Rat
- Unigene: 436446 Human
- Unigene: 29778 Mouse
- Unigene: 161941 Rat
see all
Target information above from: UniProt accession
P55145
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- Arginine rich mutated in early stage tumors antibodyArginine rich protein antibodyArginine-rich protein antibody
- ARMET antibodyARMET protein antibodyARP antibodyManf antibodyMANF_HUMAN antibodyMesencephalic astrocyte derived neurotrophic factor antibodyMesencephalic astrocyte-derived neurotrophic factor antibodyMGC142148 antibodyMGC142150 antibodyProtein ARMET antibody
see all
Anti-ARMET antibody images
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Western blot - ARMET antibody (ab67203)Lane 1 : Anti-ARMET antibody (ab67203) at 1 µg/ml
Lane 2 : Anti-ARMET antibody (ab67203) at 2 µg/ml
Lane 1 : rat brain tissue lysate
Lane 2 : rat brain tissue lysate
Predicted band size : 20 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ARMET antibody (ab67203)Ab67203 (2.5 ug/ml) staining of ARMET in human brain tissue by IHC. -
Immunocytochemistry/ Immunofluorescence-Anti-ARMET antibody(ab67203)Immunofluorescence of MANF in Human Brain cells using ab67203 at 20 ug/ml.
References for Anti-ARMET antibody (ab67203)
ab67203 has not yet been referenced specifically in any publications.
