Anti-ARMET antibody (ab77267)

Overview

• Product nameAnti-ARMET antibodySee all ARMET primary antibodies ...
• Description
  Goat polyclonal to ARMET
• Tested applicationsWB, ELISA more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat, Cow, Dog
• Immunogen

  Synthetic peptide: KFCREARGKENR, corresponding to internal sequence amino acids 59-70 of Human ARMET (vNP_006001.2).

  Run BLAST with Run BLAST with
• Positive controlHuman pancreas lysate.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.02% Sodium Azide
  Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
• Concentration information loading...
• PurityImmunogen affinity purified
• Purification notesab77267 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Cancer
  • Cell cycle
  • Cell division

  • Neuroscience
  • Neurotransmitter
  • Amino Acids
  • Other

Applications

Target

• FunctionSelectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
• Sequence similaritiesBelongs to the ARMET family.
• DomainThe N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.
• Post-translational
  modificationsMay contain sialic acid residues.
• Cellular localizationSecreted.

Target information above from: UniProt accession P55145 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 540432 Cow
  • Entrez Gene: 7873 Human
  • Entrez Gene: 74840 Mouse
  • Entrez Gene: 315989 Rat
  • Omim: 601916 Human
  • SwissProt: P80513 Cow
  • SwissProt: P55145 Human
  • SwissProt: Q9CXI5 Mouse

  • SwissProt: P0C5H9 Rat
  • Unigene: 436446 Human
  • Unigene: 29778 Mouse
  • Unigene: 161941 Rat

  see all

• Alternative names
  Arginine rich mutated in early stage tumors antibodyArginine rich protein antibodyArginine-rich protein antibody

  ARMET antibodyARMET protein antibodyARP antibodyMANF antibodyMANF_HUMAN antibodyMesencephalic astrocyte derived neurotrophic factor antibodyMesencephalic astrocyte-derived neurotrophic factor antibodyMGC142148 antibodyMGC142150 antibodyProtein ARMET antibody

  see all

Anti-ARMET antibody images

• 

  Western blot - ARMET antibody (ab77267)
  Anti-ARMET antibody (ab77267) at 0.3 µg/ml + Human Pancreas lysate (in RIPA buffer) at 35 µg
  
  Predicted band size : 20 kDa
  Observed band size : 20 kDa