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Product Name 

ARX1 antibody

Product type 

Primary antibodies

Description 

Rabbit polyclonal to ARX1

Immunogen 

Synthetic peptide derived from the N terminal domain of ARX1 (Saccharomyces cerevisiae).

Reacts with 
(species key)

Sc

Tested applications 
(see key)

ICC, WB


Abreviews 

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(see key)


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Application notes 
(see key)

Recommended dilutions
ICC: Use at an assay dependent dilution.
WB: 1/200 - 1/1000. Predicted molecular weight: 65 kDa.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Cytoplasmic and Nuclear

Research areas 

Microbiology >> Organism >> Eukaryotic Microorganism >> Yeast >> Saccharomyces spp
Signal Transduction >> Protein Trafficking >> Nuclear Import / Export
Chromatin and Nuclear Signaling >> DNA / RNA >> Translation >> Ribosome

Relevance 

Arx1 has recently been shown to be a nuclear export receptor for the 60S ribosomal subunit, in yeast. It is a nucleo cytoplasmic shuttling protein that is that is associated with pre-60S particles. It is probably involved in the proper assembly of pre ribosomal particles during the biogenesis of the 60S ribosomal subunit and accompanies the pre-60S particles to the cytoplasm and interacts directly with REI1. Arx1 does not have any peptidase activity.

 

ARX1 antibody (ab74135)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

851678    (Saccharomyces cerevisiae)

SwissProt

    

Q03862    (Saccharomyces cerevisiae)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Whole antiserum

Storage buffer 

Preservative: None
Constituents: Whole serum

Form 

Liquid

Concentration 

Concentration not determined - why is this?

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ARX1 antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to ARX1

 

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