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Product Name
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ARX1 antibody
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to ARX1
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Immunogen
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Synthetic peptide derived from the N terminal domain of ARX1 (Saccharomyces cerevisiae).
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Reacts with
(species key)
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Sc
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Tested applications
(see key)
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ICC, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions ICC: Use at an assay dependent dilution. WB: 1/200 - 1/1000. Predicted molecular weight: 65 kDa.
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasmic and Nuclear
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Research areas
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Microbiology >> Organism >> Eukaryotic Microorganism >> Yeast >> Saccharomyces spp Signal Transduction >> Protein Trafficking >> Nuclear Import / Export Chromatin and Nuclear Signaling >> DNA / RNA >> Translation >> Ribosome
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Relevance
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Arx1 has recently been shown to be a nuclear export receptor for the 60S ribosomal subunit, in yeast. It is a nucleo cytoplasmic shuttling protein that is that is associated with pre-60S particles. It is probably involved in the proper assembly of pre ribosomal particles during the biogenesis of the 60S ribosomal subunit and accompanies the pre-60S particles to the cytoplasm and interacts directly with REI1. Arx1 does not have any peptidase activity.
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Database links
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The links below go to external sites and will open in a new browser window Entrez Gene | | 851678 (Saccharomyces cerevisiae)
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| SwissProt | | Q03862 (Saccharomyces cerevisiae)
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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Preservative: None Constituents: Whole serum
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ARX1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to ARX1
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