Anti-ASB3 antibody (ab130323)

Overview

• Product nameAnti-ASB3 antibodySee all ASB3 primary antibodies ...
• Description
  Rabbit polyclonal to ASB3
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 14-42 of Human ASB3 (NP_665862.1, NP_057199.1).

• Positive controlT47D cell lysate

Properties

• FormLiquid
• Storage instructionsStore at 4°C (up to 6 months). For long term storage store at -20°C
• Storage bufferPreservative: 0.09% Sodium azide
  Constituent: 99% PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• Purification notesab130323 is purified through a protein A column, followed by peptide affinity purification.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Epigenetics and Nuclear Signaling
  • Transcription
  • Domain Families
  • Developmental Families
  • Other

  • Cell Biology
  • Cell Cycle
  • Cell Division
  • Cytokinesis

Applications

Target

• FunctionProbable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes TNFRSF1B.
• PathwayProtein modification; protein ubiquitination.
• Sequence similaritiesContains 11 ANK repeats.
  Contains 1 SOCS box domain.
• DomainThe SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.

Target information above from: UniProt accession Q9Y575 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 51130 Human
  • Omim: 605760 Human
  • SwissProt: Q9Y575 Human
  • Unigene: 40763 Human

• Alternative names
  Ankyrin repeat and SOCS box containing 3 antibodyAnkyrin repeat and SOCS box containing protein 3 antibodyAnkyrin repeat and SOCS box protein 3 antibody

  ASB 3 antibodyASB-3 antibodyASB3 antibodyASB3_HUMAN antibodyFLJ10123 antibodyFLJ10421 antibodyMGC12531 antibodyMGC132002 antibodyMGC996 antibodyOTTHUMP00000200662 antibodyWeakly similar to ankyrin brain variant 2 antibody

  see all

Anti-ASB3 antibody images

• 

  Western blot - Anti-ASB3 antibody (ab130323)
  Anti-ASB3 antibody (ab130323) at 1/100 dilution + T47D cell lysate at 35 µg
  
  Predicted band size : 58 kDa