Overview

  • Product nameAnti-ASB8 antibodySee all ASB8 primary antibodies ...
  • Description
    Mouse polyclonal to ASB8
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-288 of Human ASB8

  • Positive control
    • Transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab67895 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 35 kDa (predicted molecular weight: 32 kDa).

Target

  • FunctionMay be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  • Tissue specificityHighest level of expression in skeletal muscle. Also expressed in heart, brain, placenta, liver, kidney and pancreas.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesContains 4 ANK repeats.
    Contains 1 SOCS box domain.
  • DomainThe SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Ankyrin repeat and SOCS box containing 8 antibody
    • Ankyrin repeat and SOCS box protein 8 antibody
    • ASB 8 antibody
    • ASB-8 antibody
    • ASB8 antibody
    • ASB8_HUMAN antibody
    • FLJ21255 antibody
    • MGC5540 antibody
    • OTTHUMP00000237000 antibody
    • OTTHUMP00000237001 antibody
    • OTTHUMP00000237007 antibody
    • OTTHUMP00000237009 antibody
    • OTTHUMP00000237010 antibody
    • PP14212 antibody
    see all

Anti-ASB8 antibody images

  • All lanes : Anti-ASB8 antibody (ab67895) at 1/500 dilution

    Lane 1 : ASB8 transfected 293T cell lysate
    Lane 2 : non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 32 kDa
    Observed band size : 35 kDa (why is the actual band size different from the predicted?)

References for Anti-ASB8 antibody (ab67895)

ab67895 has not yet been referenced specifically in any publications.

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