Anti-ASF1 A+B antibody (ab53608)
Key features and details
- Rabbit polyclonal to ASF1 A+B
- Suitable for: WB
- Reacts with: Drosophila melanogaster
- Isotype: IgG
Overview
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Product name
Anti-ASF1 A+B antibody -
Description
Rabbit polyclonal to ASF1 A+B -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Drosophila melanogaster -
Immunogen
Recombinant full length protein (Fruit fly (Drosophila melanogaster))
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Constituents: 50% Glycerol, Whole serum -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab53608 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/2000. Predicted molecular weight: 24 kDa.
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Notes |
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WB
1/2000. Predicted molecular weight: 24 kDa. |
Target
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Relevance
Asf1 (anti silencing function 1) belongs to the H3/H4 family of histone chaperones. Its function has not been fully elucidated but it is believed to be involved in ensuring a constant supply of histones at sites of nucleosome assembly. Asf1 interacts with the DNA damage checkpoint protein Rad53 and so may have a role in cell cycle regulation and DNA responses. ASF1 A and B (the two human subtypes) are the only known substrate for Tousled like kinase (TLK). -
Cellular localization
Nuclear -
Alternative names
- Anti silencing factor 1 antibody
- anti-silencing function 1A antibody
- anti-silencing function 1B antibody
see all
Images
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All lanes : Anti-ASF1 A+B antibody (ab53608) at 1/2000 dilution
All lanes : Drosophila embryo lysate
Predicted band size: 24 kDa
Observed band size: 30 kDa why is the actual band size different from the predicted?
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab53608 has been referenced in 1 publication.
- Lario LD et al. ANTI-SILENCING FUNCTION1 proteins are involved in ultraviolet-induced DNA damage repair and are cell cycle regulated by E2F transcription factors in Arabidopsis. Plant Physiol 162:1164-77 (2013). PubMed: 23596192