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Products:Epigenetics and Nuclear Signaling >> Chromosome Structure >> Chromosome
Overview
Product name
Anti-ASF1 A+B antibody [ASF 4A1/3]
See all ASF1 A+B products (2) ...
Description
Mouse monoclonal [ASF 4A1/3] to ASF1 A+B
Specificity
This antibody reacts with both ASF1A and ASF1B. It recognises E coli and recombinant protein, but has not been tested on endogenous protein.
Tested applications
Cross reactivity
Reacts with
Mouse, Human
Immunogen
Full length protein ASF1A
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Monoclonal
Clone number
ASF 4A1/3
Myeloma
Sp2/0-Ag14
Isotype
IgG2a
Applications
Show applications key
Our Abpromise guarantee covers the use of ab31843 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at an assay dependent dilution. Predicted molecular weight: 23 kDa.
Target
Relevance
Asf1 (anti silencing function 1) belongs to the H3/H4 family of histone chaperones. Its function has not been fully elucidated but it is believed to be involved in ensuring a constant supply of histones at sites of nucleosome assembly. Asf1 interacts with the DNA damage checkpoint protein Rad53 and so may have a role in cell cycle regulation and DNA responses. ASF1 A and B (the two human subtypes) are the only known substrate for Tousled like kinase (TLK).
Cellular localization
Nuclear
Alternative names
- Anti silencing factor 1 antibody
- anti-silencing function 1A antibody
- anti-silencing function 1B antibody
see all
Database links
- Entrez Gene: 25842 Human
- Entrez Gene: 55723 Human
- Entrez Gene: 66403 Mouse
- Entrez Gene: 66929 Mouse
- Omim: 609189 Human
- Omim: 609190 Human
- SwissProt: Q9NVP2 Human
- SwissProt: Q9Y294 Human
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References for Anti-ASF1 A+B antibody [ASF 4A1/3] (ab31843)
ab31843 has not yet been referenced specifically in any publications.
Publishing research using ab31843? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"