Anti-ASK1 (phospho S966) antibody (ab39402)
- Product nameAnti-ASK1 (phospho S966) antibodySee all ASK1 primary antibodies ...
- DescriptionRabbit polyclonal to ASK1 (phospho S966)
- Specificityab39402 detects endogenous levels of ASK1 only when phosphorylated at Serine 966.
- Tested applicationsELISA, IHC-P more details
- Species reactivityReacts with: Human
Predicted to work with: Mouse
Synthetic phosphopeptide: SISpLP, derived from Human ASK1 around the phosphorylation site of Serine 966
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
- Concentration information loading...
- PurityImmunogen affinity purified
- Purification notesab39402 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific phosphopeptide. The antibody against non phosphopeptide was removed by chromatography using non phosphopeptide corresponding to the phosphorylation site.
- Clonality Polyclonal
- Research Areas
Our Abpromise guarantee covers the use of ab39402 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||IHC-P: Use at an assay dependent dilution.|
- FunctionComponent of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.
- Tissue specificityAbundantly expressed in heart and pancreas.
- Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Contains 1 protein kinase domain.
modificationsDephosphorylated and activated by PGAM5.
- Apoptosis signal regulating kinase 1 antibodyApoptosis signal-regulating kinase 1 antibodyASK 1 antibody
- ASK-1 antibodyASK1 antibodyM3K5 antibodyM3K5_HUMAN antibodyMAP/ERK kinase kinase 5 antibodyMAP3K5 antibodyMAPK/ERK kinase kinase 5 antibodyMAPKKK5 antibodyMEK kinase 5 antibodyMEKK 5 antibodyMEKK5 antibodyMitogen activated protein kinase kinase kinase 5 antibodyMitogen-activated protein kinase kinase kinase 5 antibody
Anti-ASK1 (phospho S966) antibody images
ab39402, at a 1/100 dilution, staining human ASK1 in breast carcinoma tissue by Immunohistochemistry, Paraffin embedded tissue.
ab39402, at a 1/100 dilution, staining human ASK1 in breast carcinoma tissue (treated with synthesized phosphopeptide) by Immunohistochemistry, Paraffin embedded tissue.
References for Anti-ASK1 (phospho S966) antibody (ab39402)
ab39402 has not yet been referenced specifically in any publications.