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Products:Signal Transduction >> Metabolism >> Plasma Membrane >> ATPases
Overview
Product name
Anti-ATAD2 antibody
See all ATAD2 products (2) ...
Description
Mouse polyclonal to ATAD2
Specificity
This antibody is reactive against mammalian transfected lysate.
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
ATAD2 (AAH19909.1, 1 a.a. ~ 362 a.a) full-length human protein.
Positive control
Transfected 293T cell lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 1X PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> Transcription >> Bromodomain containing
Signal Transduction >> Protein Trafficking >> Chaperones >> Other Chaperones
Signal Transduction >> Metabolism >> Plasma Membrane >> ATPases
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Western blot - ATAD2 antibody (ab68019)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab68019 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500 - 1/1000.Detects a band of approximately 45 kDa.
Target
Function
May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
Tissue specificity
Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors.
Sequence similarities
Belongs to the AAA ATPase family.
Contains 1 bromo domain.
Cellular localization
Nucleus.
Target information above from: UniProt accessionQ6PL18
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- AAA nuclear coregulator cancer-associated protein antibody
- ANCCA antibody
- Atad2 antibody
see all
Database links
- Entrez Gene: 29028 Human
- Omim: 611941 Human
- SwissProt: Q6PL18 Human
- Unigene: 370834 Human
Anti-ATAD2 antibody images:
Western blot - ATAD2 antibody (ab68019)
All lanes : Anti-ATAD2 antibody (ab68019) at 1/500 dilution
Lane 1 : ATAD2 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 1/500 dilution per lane.
Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Observed band size : 45 kDa (why is the actual band size different from the predicted?)
References for Anti-ATAD2 antibody (ab68019)
ab68019 has not yet been referenced specifically in any publications.
Publishing research using ab68019? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"