Overview
Product nameATBF1 protein (His-DHFR tag)
Protein descriptionRecombinant fragment of Human ATBF1 (amino acids 517-787) with N terminal His-DHFR tag, 29kDa (calculated without tag). (UniProt ID = Q8N2Y6).
Uniprot accessionQ8N2Y6
Molecular weight29kDa
Protein length271 amino acids
Expression hostE. coli
Properties
Purification notesPurity is 70% by SDS-PAGE.
FormLyophilised:Reconstitute with water to desired concentration.
Storage instructionsShipped at 4°C. Store at -20ºC.
Storage bufferConstituents: 0.32% Tris HCl, 0.58% Sodium chloride
Concentration information loading...
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab127446
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Application
|
Notes |
| SDS-PAGE |
SDS-PAGE: Use at an assay dependent dilution. |
Protein info
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Alternative names
Alpha fetoprotein enhancer binding proteinAT binding transcription factor 1AT motif binding factor
see all
RelevanceATBF1 is a transcription factor that negatively regulates alpha fetoprotein and MYB, transactivates CDKN1A, and may be a tumor suppressor. Loss of ATBF1 is one mechanism that defines the absence of growth control in prostate cancer. Presence of the isoform ABTF1-A is correlated with better prognosis in breast cancer and may also serve as a marker of endocrine responsiveness.
Cellular localizationNuclear
References for ATBF1 protein (His-DHFR tag) (ab127446)
ab127446
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
