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Products:Epigenetics and Nuclear Signaling >> Transcription >> Other factors
Overview
Product name
Anti-ATF3 antibody
See all ATF3 products (4) ...
Description
Mouse monoclonal to ATF3
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 1-182 of Human ATF3
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG3
Light chain type
kappa
Research areas
Cancer >> Tumor biomarkers >> Other
Epigenetics and Nuclear Signaling >> Transcription >> Other factors
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Western blot - ATF3 antibody (ab54854)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab54854 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
Sequence similarities
Belongs to the bZIP family. ATF subfamily.
Contains 1 bZIP domain.
Cellular localization
Nucleus.
Target information above from: UniProt accessionP18847
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Activating transcription factor 3 antibody
- ATF3 antibody
- ATF3_HUMAN antibody
see all
Database links
- Entrez Gene: 467 Human
- Omim: 603148 Human
- SwissProt: P18847 Human
- Unigene: 460 Human
Anti-ATF3 antibody images:
Western blot - ATF3 antibody (ab54854)
Anti-ATF3 antibody (ab54854)
Predicted band size : 21 kDa
ATF3 antibody (ab54854) at 1ug/lane + HeLa cell lysate at 25ug/lane.
References for Anti-ATF3 antibody (ab54854)
ab54854 has not yet been referenced specifically in any publications.
Publishing research using ab54854? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"