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Western blot - ATF3 antibody (ab54854)
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Product Name
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ATF3 antibody
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See all ATF3 antibodies (4)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to ATF3
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Immunogen
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Recombinant full length protein, corresponding to amino acids 1-182 of Human ATF3
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Reacts with
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Hu
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Tested applications
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WB
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Abreviews
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Application notes
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear
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Research areas
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Cancer >> Tumor biomarkers >> Other
Chromatin and Nuclear Signaling >> Transcription >> Other factors
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Relevance
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Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. It encodes a protein with a calculated molecular mass of 22 kD. ATF3 represses rather than activates transcription from promoters with ATF binding elements. An alternatively spliced form of ATF3 (ATF3 delta Zip) encodes a truncated form ATF3 protein lacking the leucine zipper protein-dimerization motif and does not bind to DNA. In contrast to ATF3, ATF3 delta Zip stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. Three transcript variants encoding two different isoforms have been found for this gene.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG3
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ATF3 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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ATF3 antibody images:
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 Western blot - ATF3 antibody (ab54854)
ATF3 antibody (ab54854)
Predicted band size : 21 kDa
ATF3 antibody (ab54854) at 1ug/lane + HeLa cell lysate at 25ug/lane.
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Search PubMed (MEDLINE) for references to ATF3
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ATF3 antibody - more information
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Customer reviews (feedback) regarding ATF3 antibody |
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Protocols for ATF3 antibody |
Price and availability of products related to ATF3 antibody |
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ATF3 antibody - other tools:
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Contact Abcam with a Technical Enquiry about ATF3 antibody |
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