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Western blot - ATF3 antibody (ab54854)
Western blot - ATF3 antibody (ab54854)
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Product Name 

ATF3 antibody

 

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Product type 

Primary antibodies

Description 

Mouse monoclonal to ATF3

Immunogen 

Recombinant full length protein, corresponding to amino acids 1-182 of Human ATF3

Reacts with 
(species key)

Hu

Tested applications 
(see key)

WB


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Nuclear

Research areas 

Cancer >> Tumor biomarkers >> Other
Chromatin and Nuclear Signaling >> Transcription >> Other factors

Relevance 

Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. It encodes a protein with a calculated molecular mass of 22 kD. ATF3 represses rather than activates transcription from promoters with ATF binding elements. An alternatively spliced form of ATF3 (ATF3 delta Zip) encodes a truncated form ATF3 protein lacking the leucine zipper protein-dimerization motif and does not bind to DNA. In contrast to ATF3, ATF3 delta Zip stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. Three transcript variants encoding two different isoforms have been found for this gene.

 

ATF3 antibody (ab54854)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

467    (Human)

Omim

    

603148    (Human)

SwissProt

    

P18847    (Human)

Unigene

    

460    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Isotype 

IgG3

Light chain type 

kappa

Purity 

Protein G purified

Storage buffer 

Preservative: None
PBS, pH 7.2

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ATF3 antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

ATF3 antibody images:

Product image  Western blot - ATF3 antibody (ab54854)

Western blot - ATF3 antibody (ab54854)

ATF3 antibody (ab54854)

Predicted band size : 21 kDa


ATF3 antibody (ab54854) at 1ug/lane + HeLa cell lysate at 25ug/lane.

 
 

Search PubMed (MEDLINE) for references to ATF3

 

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