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Products:Epigenetics and Nuclear Signaling >> Transcription >> Other factors
Overview
Product name
Anti-ATF3 antibody
See all ATF3 products (4) ...
Description
Rabbit polyclonal to ATF3
Tested applications
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Rat, Chicken, Cow, Dog
Immunogen
Synthetic peptide corresponding to a region within internal amino acids 72 - 121 (LGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEK TECLQKESEKL) of Human ATF3 (NP_001665)
LGVSITKAEV APEEDERKKR RRERNKIAAA KCRNKKKEKT ECLQKESEKL
Positive control
OVCAR-3 cell lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 2% Sucrose, PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Tumor biomarkers >> Other
Epigenetics and Nuclear Signaling >> Transcription >> Other factors
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Western blot - ATF3 antibody (ab87213)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab87213 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 µg/mlPredicted molecular weight: 21 kDa.
Target
Function
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
Sequence similarities
Belongs to the bZIP family. ATF subfamily.
Contains 1 bZIP domain.
Cellular localization
Nucleus.
Target information above from: UniProt accessionP18847
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Activating transcription factor 3 antibody
- ATF3 antibody
- ATF3_HUMAN antibody
see all
Database links
- Entrez Gene: 467 Human
- Entrez Gene: 11910 Mouse
- Entrez Gene: 25389 Rat
- Omim: 603148 Human
- SwissProt: P18847 Human
- SwissProt: Q60765 Mouse
- SwissProt: P29596 Rat
- Unigene: 460 Human
see all
Anti-ATF3 antibody images:
Western blot - ATF3 antibody (ab87213)
Anti-ATF3 antibody (ab87213) at 1 µg/ml (in 5% skim milk / PBS buffer) + OVCAR-3 cell lysate at 10 µg
Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution
Predicted band size : 21 kDa
Gel concentration: 12%
References for Anti-ATF3 antibody (ab87213)
ab87213 has not yet been referenced specifically in any publications.
Publishing research using ab87213? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"