Anti-ATG4B antibody (ab64737)

Overview

• Product nameAnti-ATG4B antibodySee all ATG4B primary antibodies ...
• Description
  Sheep polyclonal to ATG4B
• Tested applicationsWB, IHC-P, IHC-Fr more details
• Species reactivity
  Reacts with: Mouse, Human
  
• Immunogen

  Synthetic peptide common to human and mouse ATG4B, conjugated to an immunogenic carrier protein.

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C (add glycerol to a final volume of 50% for extra stability). Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: PBS, Whole serum
• PurityWhole antiserum
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Pathways and Processes
  • Metabolism processes
  • Autophagy and mitophagy
  • APG gene products

  • Cancer
  • Invasion/microenvironment
  • ECM
  • Extracellular matrix
  • Other

  • Cancer
  • Signal transduction
  • Autophagy

  • Cardiovascular
  • Heart
  • Autophagy
  • APG gene products

  • Cell Biology
  • Proteolysis / Ubiquitin
  • Proteolytic enzymes
  • Other proteases

Applications

Target

• FunctionCysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
• Tissue specificityMainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas.
• Sequence similaritiesBelongs to the peptidase C54 family.
• Cellular localizationCytoplasm.

Target information above from: UniProt accession Q9Y4P1 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 23192 Human
  • Entrez Gene: 66615 Mouse
  • Omim: 611338 Human
  • SwissProt: Q9Y4P1 Human
  • SwissProt: Q8BGE6 Mouse
  • Unigene: 283610 Human
  • Unigene: 29087 Mouse

• Alternative names
  APG4 autophagy 4 homolog B antibodyAPG4B antibodyATG4 autophagy related 4 homolog B (S. cerevisiae) antibody

  ATG4B antibodyATG4B_HUMAN antibodyAUT like 1 cysteine endopeptidase antibodyAUT-like 1 cysteine endopeptidase antibodyAUTL1 antibodyAutophagin 1 antibodyAutophagin-1 antibodyAutophagy related cysteine endopeptidase 1 antibodyAutophagy related protein 4 homolog B antibodyAutophagy-related cysteine endopeptidase 1 antibodyAutophagy-related protein 4 homolog B antibodyCysteine protease ATG4B antibodyhAPG4B antibodyMGC1353 antibody

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