Overview

  • Product nameAnti-ATG4D antibodySee all ATG4D primary antibodies ...
  • Description
    Sheep polyclonal to ATG4D
  • Tested applicationsWB, IHC-P, IHC-Fr more details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Monkey
  • Immunogen

    Synthetic peptide from human ATG4D, conjugated to an immunogenic carrier protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab64735 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB 1/200 - 1/3000. Predicted molecular weight: 53 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
IHC-P 1/200 - 1/3000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
IHC-Fr 1/200 - 1/3000.

Target

  • FunctionCysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
  • Tissue specificityMainly expressed in skeletal muscle and, to a lower extent, in testis.
  • Sequence similaritiesBelongs to the peptidase C54 family.
  • Cellular localizationCytoplasm.
  • Target information above from: UniProt accession Q86TL0 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • Alternative names
    • 9830134P12Rik antibody
    • APG4 autophagy 4 homolog D antibody
    • APG4 D antibody
    • APG4, S. cerevisiae, homolog of, D antibody
    • APG4D antibody
    • ATG4 autophagy related 4 homolog D (S. cerevisiae) antibody
    • Atg4d antibody
    • ATG4D_HUMAN antibody
    • Atg4dl antibody
    • AUT like 4 cysteine endopeptidase antibody
    • AUT-like 4 cysteine endopeptidase antibody
    • AUTL4 antibody
    • Autophagin 4 antibody
    • Autophagin-4 antibody
    • autophagy 4, S. cerevisiae, homolog of, D antibody
    • autophagy related 4D, cysteine peptidase antibody
    • Autophagy related cysteine endopeptidase 4 antibody
    • Autophagy related protein 4 homolog D antibody
    • Autophagy-related cysteine endopeptidase 4 antibody
    • Autophagy-related protein 4 homolog D antibody
    • Cysteine protease ATG4D antibody
    • Cysteine protease involved in autophagy antibody
    • MGC31226 antibody
    see all

References for Anti-ATG4D antibody (ab64735)

ab64735 has not yet been referenced specifically in any publications.

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