Anti-ATP13A2 antibody (ab43075)

Overview

• Product nameAnti-ATP13A2 antibodySee all ATP13A2 primary antibodies ...
• Description
  Rabbit polyclonal to ATP13A2
• Tested applicationsIHC-Fr more details
• Species reactivity
  Reacts with: Rat, Human
  Predicted to work with: Mouse
• Immunogen

  Synthetic peptide: C-DDVHRSRHGLSLQDQ, corresponding to amino acids 195-209 of Human ATP13A2.

  Run BLAST with Run BLAST with
• Positive controlRat peripheral sensory ganglia.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• PurityWhole antiserum
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Neurodegenerative disease

  • Metabolism
  • Types of disease
  • Cancer

  • Signal Transduction
  • Metabolism
  • Plasma Membrane
  • ATPases

  • Neuroscience
  • Neurology process
  • Neurodegenerative disease
  • Parkinson's disease
  • Parkin / PARK

  • Neuroscience
  • Neurology process
  • Neurodegenerative disease
  • Other

Applications

Target

• Involvement in diseaseDefects in ATP13A2 are the cause of Kufor-Rakeb syndrome (KRS) [MIM:606693]; also known as Parkinson disease type 9 (PARK9). KRS is a rare hereditary disease with juvenile onset. In addition to typical signs of Parkinson disease, affected individuals show symptoms of more widespread neurodegeneration, including dementia.
• Sequence similaritiesBelongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
• Cellular localizationMembrane.

Target information above from: UniProt accession Q9NQ11 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 23400 Human
  • Entrez Gene: 23400 Human
  • Entrez Gene: 74772 Mouse
  • Entrez Gene: 362645 Rat
  • Omim: 610513 Human
  • SwissProt: Q9NQ11 Human
  • SwissProt: Q9NQ11 Human
  • SwissProt: Q9CTG6 Mouse

  • Unigene: 128866 Human
  • Unigene: 205625 Mouse
  • Unigene: 19659 Rat

  see all

• Alternative names
  AT132_HUMAN antibodyAtp13a2 antibodyATPase type 13A2 antibody

  CLN12 antibodyFLJ26510 antibodyHSA9947 antibodyKRPPD antibodyPARK9 antibodyProbable cation transporting ATPase 13A2 antibodyProbable cation-transporting ATPase 13A2 antibodyPutative ATPase antibodyRP1-37C10.4 antibody

  see all

Anti-ATP13A2 antibody images

• 

  Immunohistochemistry (Frozen sections) - ATP13A2 antibody (ab43075)
  Ab43075 staining ATP13A2 by immunohistochemistry using frozen tissue.

  The cryostat section of the rat spinal cord was incubated in ab43075 to the human ATPase protein at the dilution of 1:1000 overnight followed with a biotinylated secondary antibody and ABC kit. The section was developed in diaminobenzidine solution and enhanced in the presence of nickel sulphate. Cell bodies and nerve fibers in the trigeminal nerve are stained.