Anti-ATP synthase C antibody (ab96655)
Key features and details
- Rabbit polyclonal to ATP synthase C
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
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- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-ATP synthase C antibody
See all ATP synthase C primary antibodies -
Description
Rabbit polyclonal to ATP synthase C -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human ATP synthase C. Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ATP synthase C. The immunogen includes the transit peptide (aa 1-61).
Database link: P05496 -
Positive control
- Molt-4 whole cell lysate and Raji cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 59.99% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96655 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 14 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 14 kDa. |
Target
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Function
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. -
Sequence similarities
Belongs to the ATPase C chain family. -
Cellular localization
Mitochondrion membrane. - Information by UniProt
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Database links
- Entrez Gene: 516 Human
- Entrez Gene: 517 Human
- Entrez Gene: 518 Human
- Omim: 602736 Human
- Omim: 603192 Human
- Omim: 603193 Human
- SwissProt: P05496 Human
- SwissProt: P48201 Human
see all -
Alternative names
- AT5G1_HUMAN antibody
- ATP synthase c subunit antibody
- ATP synthase F(0) complex subunit C1, mitochondrial antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (6)
ab96655 has been referenced in 6 publications.
- Zhang K et al. ATP synthase inhibitory factor subunit 1 regulates islet β-cell function via repression of mitochondrial homeostasis. Lab Invest 102:69-79 (2022). PubMed: 34608240
- Lewis CJ et al. Codon optimization is an essential parameter for the efficient allotopic expression of mtDNA genes. Redox Biol 30:101429 (2020). WB ; Human . PubMed: 31981894
- Zhu G et al. Acute effect of lactic acid on tumor-endothelial cell metabolic coupling in the tumor microenvironment. Oncol Lett 12:3478-3484 (2016). WB ; Human . PubMed: 27900024
- Xu XD et al. The study of energy metabolism in bladder cancer cells in co-culture conditions using a microfluidic chip. Int J Clin Exp Med 8:12327-36 (2015). PubMed: 26550142
- Alavian KN et al. An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore. Proc Natl Acad Sci U S A 111:10580-5 (2014). WB ; Human . PubMed: 24979777
- De Marchi E et al. The mitochondrial permeability transition pore is a dispensable element for mitochondrial calcium efflux. Cell Calcium 56:1-13 (2014). WB ; Human . PubMed: 24755650