Anti-ATRIP (phospho S68) antibody (ab182626)
Key features and details
- Rabbit polyclonal to ATRIP (phospho S68)
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-ATRIP (phospho S68) antibody
See all ATRIP primary antibodies -
Description
Rabbit polyclonal to ATRIP (phospho S68) -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Synthetic peptide within Human ATRIP aa 50-150 (phospho S68) conjugated to keyhole limpet haemocyanin. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: Q8WXE1 -
Positive control
- 3T3 cell line lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
without Mg2+ and Ca2+ -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab182626 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/1000. Predicted molecular weight: 86 kDa.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 86 kDa. |
Target
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Function
Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein. -
Tissue specificity
Ubiquitous. -
Sequence similarities
Belongs to the ATRIP family. -
Domain
The EEXXXDDL motif is required for the interaction with catalytic subunit PRKDC and its recruitment to sites of DNA damage. -
Post-translational
modificationsPhosphorylated by ATR. -
Cellular localization
Nucleus. Redistributes to discrete nuclear foci upon DNA damage. - Information by UniProt
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Database links
- Entrez Gene: 235610 Mouse
- SwissProt: Q8BMG1 Mouse
- Unigene: 100622 Mouse
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Alternative names
- AGS1 antibody
- ATIP antibody
- ATM and Rad3 related interacting protein antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab182626 has not yet been referenced specifically in any publications.