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Overview

  • Product nameAcidic Calponin protein (Human)See all Acidic Calponin proteins and peptides ...
  • Protein descriptionRecombinant fragment of Human Acidic Calponin (amino acids 230-329) with N terminal proprietary tag. Predicted MW 36.63 kDa (UniProt: Q15417).
  • Uniprot accessionQ15417
  • Molecular weight36.630kDa inclusive of tags
  • Protein length100 amino acids
  • Expression hostWheat germ

    • Properties

  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage bufferpH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl
  • Concentration information loading...
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • SequenceDQKLTLQPVDNSTISLQMGTNKVASQKGMSVYGLGRQVYD PKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQAEYPDEYH GEYQDDYPRDYQYSDQGIDY
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab116869 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent concentration.
    WB WB: Use at an assay dependent concentration. Recombinant protein.
    ELISA ELISA: Use at an assay dependent concentration.

    Protein info

    • Alternative names
        Acidic calponin 3acidic isoformCalponin
        Calponin 3Calponin 3 acidicCalponin acidicCalponin acidic isoformCalponin-3Calponin3CNN 3Cnn3CNN3_HUMANdJ639P13.2.2OTTHUMP00000012470OTTHUMP00000012471
      see all
  • FunctionThin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
  • Tissue specificityExpressed in both non-smooth muscle tissues as well as smooth muscle tissues.
  • Sequence similaritiesBelongs to the calponin family.
    Contains 3 calponin-like repeats.
    Contains 1 CH (calponin-homology) domain.

    • Target information above from: UniProt accession Q15417 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    Acidic Calponin protein (Human) images

    • SDS-PAGE - Acidic Calponin protein (Human) (ab116869)
      SDS-PAGE - Acidic Calponin protein (Human) (ab116869)
      12.5% SDS-PAGE stained with Coomassie Blue showing ab116869 at approximately 36.63 kDa.

    References for Acidic Calponin protein (Human) (ab116869)

    ab116869 has not yet been referenced specifically in any publications.

    Publishing research using ab116869 ? Please let us know so that we can cite the reference in this datasheet

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