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Overview

  • Product nameAnti-Acinus antibodySee all Acinus primary antibodies ...
  • Description
    Rabbit polyclonal to Acinus
  • Tested applicationsWB, ELISA more details
  • Species reactivity
    Reacts with: Rat, Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide corresponding to N-terminal residues of human Acinus

Properties

Applications

Our Abpromise guarantee covers the use of ab55938 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: Use a concentration of 1 µg/ml. Predicted molecular weight: 152 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA ELISA: Use at an assay dependent dilution.

Target

  • FunctionComponent of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesContains 1 SAP domain.
  • Post-translational
    modifications    Undergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.
  • Cellular localizationNucleus.

    • Target information above from: UniProt accession Q9UKV3 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    see all
  • Alternative names
      ACIN 1 antibodyACIN1 antibodyACINU_HUMAN antibody
      ACINUS antibodyACN antibodyApoptotic chromatin condensation inducer 1 antibodyApoptotic chromatin condensation inducer in the nucleus antibodyDKFZp667N107 antibodyfSAP152 antibodyfunctional spliceosome-associated protein 152 antibodyKIAA0670 antibody
    see all

References for Anti-Acinus antibody (ab55938)

ab55938 has not yet been referenced specifically in any publications.

Publishing research using ab55938 ? Please let us know so that we can cite the reference in this datasheet

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