Overview

  • Product nameAnti-Acinus antibodySee all Acinus primary antibodies ...
  • Description
    Rabbit polyclonal to Acinus
  • Tested applicationsWB, ELISA more details
  • Species reactivity
    Reacts with: Rat, Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide corresponding to N-terminal residues of human Acinus

Properties

Applications

Our Abpromise guarantee covers the use of ab55938 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 152 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

Target

  • FunctionComponent of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesContains 1 SAP domain.
  • Post-translational
    modifications
    Undergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.
  • Cellular localizationNucleus.
  • Target information above from: UniProt accession Q9UKV3 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • Alternative names
    • ACIN 1 antibody
    • ACIN1 antibody
    • ACINU_HUMAN antibody
    • ACINUS antibody
    • ACN antibody
    • Apoptotic chromatin condensation inducer 1 antibody
    • Apoptotic chromatin condensation inducer in the nucleus antibody
    • DKFZp667N107 antibody
    • fSAP152 antibody
    • functional spliceosome-associated protein 152 antibody
    • KIAA0670 antibody
    see all

References for Anti-Acinus antibody (ab55938)

ab55938 has not yet been referenced specifically in any publications.

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