Overview
Product nameAcinus peptideSee all Acinus proteins and peptides ...
Properties
FormLiquid
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferPBS with 0.1% BSA 0.02% sodium azide pH7.2
Concentration information loading...
Sequence notesTRTALHGVKWPQSNPK
corresponding to amino acids 1065 to 1080 of humanAcinusL, 338 to 353 of human AcinusS’, or 307 to 322 ofhuman AcinusS, which are identical to those of mouseAcinus. The selected antigenic sequence is locatednear the C-terminus of the cleaved active peptide p17.
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab8367
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Application
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Notes |
| Blocking |
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Application notesThe peptide is used for blocking the antibody activity of Acinus (catalog number ab7352). Itusually blocks the antibody activity completely in Western blot by incubating the peptide withequal volume of antibody for 30 min at 37°C
Protein info
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Alternative names
AcinusACNApoptotic chromatin condensation inducer 1Apoptotic chromatin condensation inducer in the nucleusApoptotic chromatin condensation inducer in the nucleusDKFZp667N107fSAP152functional spliceosome-associated protein 152KIAA0670
see all
FunctionComponent of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
Tissue specificityUbiquitous.
Sequence similaritiesContains 1 SAP domain.
Post-translational
modificationsUndergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.
Cellular localizationNucleus.
References for Acinus peptide (ab8367)
ab8367
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
