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Overview

  • Product nameAcinus peptideSee all Acinus proteins and peptides ...

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPBS with 0.1% BSA 0.02% sodium azide pH7.2
  • Concentration information loading...
  • Sequence notesDTSENRPENDVPEPP Amino acids 775 to 789 of human AcinusL, 48 to 62 of human AcinusS’, or 17 to 31of human AcinusS (1).
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab8369 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Blocking
  • Application notesThe peptide is used for blocking the antibody activity of Acinus ab7354. Itusually blocks the antibody activity completely in Western blot by incubating the peptide withequal volume of antibody for 30 min at 37°C

    • Protein info

    • Alternative names
        ACIN 1ACIN1ACINU_HUMAN
        AcinusACNApoptotic chromatin condensation inducer 1Apoptotic chromatin condensation inducer in the nucleusApoptotic chromatin condensation inducer in the nucleusDKFZp667N107fSAP152functional spliceosome-associated protein 152KIAA0670
      see all
  • FunctionComponent of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesContains 1 SAP domain.
  • Post-translational
    modifications    Undergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.
  • Cellular localizationNucleus.

    • Target information above from: UniProt accession Q9UKV3 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for Acinus peptide (ab8369)

    ab8369 has not yet been referenced specifically in any publications.

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