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Western blot - Aconitase 1 antibody (ab54718)
(enlarge)
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Product Name
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Aconitase 1 antibody
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See all Aconitase 1 antibodies (6)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to Aconitase 1
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Immunogen
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Recombinant fragment, corresponding to amino acids 780-890 of Human Aconitase 1
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Reacts with
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RecFrag
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Predicted to react
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Hu
(Due to sequence homology)
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Tested applications
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WB
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Abreviews
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Application notes
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasmic
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Research areas
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Signal Transduction >> Metabolism >> Vitamins / Minerals
Chromatin and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
Signal Transduction >> Metabolism >> Energy Metabolism
Cardiovascular >> Blood >> Other
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Relevance
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Aconitase 1 (ACO1) also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IRES). IREs are translational regulatory sequences found in the 5'-UTR of ferritin, and in the 3'-UTR of transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis by regulating ferritin mRNA translation and TFRC mRNA stability.
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Database links
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The links below go to external sites and will open in a new browser window Entrez Gene | | 48 (Human)
| Omim | | 100880 (Human)
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG2a
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Aconitase 1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for Aconitase 1 antibody images, references, products related to ab54718 and other tools.
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Aconitase 1 antibody images:
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 Western blot - Aconitase 1 antibody (ab54718)
Western blot against tagged recombinant protein immunogen using ab54718 Aconitase 1 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
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Search PubMed (MEDLINE) for references to Aconitase 1
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Aconitase 1 antibody - more information
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