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Actin Regulatory Protein CAPG protein (His tag) (ab40615)

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Overview

  • Product nameActin Regulatory Protein CAPG protein (His tag)See all Actin Regulatory Protein CAPG proteins and peptides ...
  • Protein descriptionRecombinant full length Macrophage capping protein (Human).His-Tag at N-terminus.
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • FormLiquid
  • Storage instructionsAliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.002% Sodium Azide
    Constituents: 3mM Sodium chloride, 10mM Tris, 2.5 mM Imidazole, pH 8.0
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab40615 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    MS MS: Use at an assay dependent dilution.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
  • Application notesThis peptide can be used with studies using ab155688.

    • Protein info

    • Alternative names
        Actin capping protein GCAP39Actin regulatory protein CAP GActin regulatory protein CAP-G
        AFCPCapgCAPG_HUMANCapping protein (actin filament) gelsolin likeCapping protein gelsolin likegCap39Gelsolin like capping proteinMacrophage capping proteinMacrophage-capping proteinmbh1MCPMyc basic motif homolog 1
      see all
  • FunctionCalcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
  • Tissue specificityMacrophages and macrophage-like cells.
  • Sequence similaritiesBelongs to the villin/gelsolin family.
    Contains 3 gelsolin-like repeats.
  • Post-translational
    modifications    The N-terminus is blocked.
  • Cellular localizationCytoplasm. Nucleus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

    • Target information above from: UniProt accession P40121 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    Actin Regulatory Protein CAPG protein (His tag) images

    • Western blot - Actin Regulatory Protein CAPG protein (His tag) (ab40615)
      Western blot - Actin Regulatory Protein CAPG protein (His tag) (ab40615)

    References for Actin Regulatory Protein CAPG protein (His tag) (ab40615)

    ab40615 has not yet been referenced specifically in any publications.

    Publishing research using ab40615 ? Please let us know so that we can cite the reference in this datasheet

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