Recombinant human Cathepsin L/MEP protein (ab198444)
Key features and details
- Expression system: Mammalian
- Purity: > 80% SDS-PAGE
- Active: Yes
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE, Functional Studies
Description
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Product name
Recombinant human Cathepsin L/MEP protein
See all Cathepsin L/MEP proteins and peptides -
Biological activity
Specific Activity: ≥ 990 pmol/min/µg
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Purity
> 80 % SDS-PAGE. -
Expression system
Mammalian -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
TLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYR EGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRS VDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLV DCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKY SVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEP DCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKD RRNHCGIASAASYPTV -
Predicted molecular weight
36 kDa including tags -
Amino acids
18 to 333 -
Tags
His tag C-Terminus -
Additional sequence information
This product is for the mature full length protein from aa 18 to 333. The signal peptide is not included.
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab198444 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
Functional Studies
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Form
Liquid -
Additional notes
Expressed in FreeStyle 293-F cells.
Useful for activation of DPP1 (Cathepsin C). Suitable for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Preservative: 1.36% Imidazole
Constituents: 20% Glycerol (glycerin, glycerine), 0.63% Tris HCl, 0.02% Potassium chloride, 0.64% Sodium chloride, 0.05% (R*,R*)-1,4-Dimercaptobutan-2,3-diolThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- Cathepsin L
- cathepsin L, 1 b
- Cathepsin L1
see all -
Function
Important for the overall degradation of proteins in lysosomes. -
Sequence similarities
Belongs to the peptidase C1 family. -
Cellular localization
Lysosome. - Information by UniProt
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab198444 has not yet been referenced specifically in any publications.