Native human Chymotrypsin protein (ab90927)
Key features and details
- Expression system: Native
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
Description
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Product name
Native human Chymotrypsin protein
See all Chymotrypsin proteins and peptides -
Biological activity
Activity: 40-70 units per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one µmole of Suc-Ala-Ala-Pro-Phe-pNA per minute at 25°C, pH 8.0 -
Purity
> 95 % SDS-PAGE. -
Expression system
Native -
Protein length
Full length protein -
Animal free
No -
Nature
Native -
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Species
Human
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Specifications
Our Abpromise guarantee covers the use of ab90927 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Functional Studies
SDS-PAGE
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Form
Lyophilized -
Additional notes
Prepared from tissue shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20ºC.
Constituent: 0.0072% Hydrochloric acid
This product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- Caldecrin
- Chymotrypsin C
- Chymotrypsin-C
see all -
Function
Has chymotrypsin-type protease activity and hypocalcemic activity. -
Tissue specificity
Pancreas. -
Involvement in disease
Variations in CTRC influence susceptibility to chronic pancreatitis [MIM:167800]. Chronic pancreatitis is a persistent inflammatory disorder characterized by permanent destruction of the pancreatic parenchyma. -
Sequence similarities
Belongs to the peptidase S1 family. Elastase subfamily.
Contains 1 peptidase S1 domain. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (1)
ab90927 has been referenced in 1 publication.
- Borberg E et al. Ultrafast one-minute electronic detection of SARS-CoV-2 infection by 3CLpro enzymatic activity in untreated saliva samples. Nat Commun 13:6375 (2022). PubMed: 36289211