Recombinant human IL-2 protein (ab119439)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: WB, ELISA, Functional Studies, SDS-PAGE, HPLC
Description
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Product name
Recombinant human IL-2 protein
See all IL-2 proteins and peptides -
Biological activity
1 x 107 units/mg
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Purity
> 98 % SDS-PAGE.
Purity >98% by SDS PAGE and HPLC sequence analysis. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Predicted molecular weight
15 kDa -
Amino acids
21 to 153
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab119439 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
Functional Studies
SDS-PAGE
HPLC
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Form
Lyophilized -
Additional notes
Endotoxin Level: <0.1 ng/ug
Store at -20°C prior to reconstitution -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle. Reconstitute for long term storage.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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ReconstitutionReconstitute with 0.1ml 0.1M acetic acid. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.
General Info
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Alternative names
- Aldesleukin
- IL 2
- IL-2
see all -
Function
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. -
Involvement in disease
Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. -
Sequence similarities
Belongs to the IL-2 family. -
Cellular localization
Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (1)
ab119439 has been referenced in 1 publication.
- Xie L et al. P108 and T109 on E2 Glycoprotein Domain I Are Critical for the Adaptation of Classical Swine Fever Virus to Rabbits but Not for Virulence in Pigs. J Virol 94:N/A (2020). PubMed: 32581110