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Activin A Receptor Type IB protein (Tagged) (ab132045)

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Overview

  • Product nameActivin A Receptor Type IB protein (Tagged)See all Activin A Receptor Type IB proteins and peptides ...
  • Protein descriptionRecombinant full length Human Activin A Receptor Type IB (amino acids 1-505) with N terminal proprietary tag; Predicted MWt 81.29 kDa (inclusive of tag).
  • Uniprot accessionP36896
  • Molecular weight81.290kDa inclusive of tags
  • Protein length505 amino acids
  • Expression hostWheat germ

    • Properties

  • E.C. Number2.7.11.30
  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage bufferpH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl
  • Concentration information loading...
  • Additional notesProtein concentration is above or equal to 0.05 µg/µl.
    Best used within three months from the date of receipt.
  • Sequence notesMAESAGASSFFPLVVLLLAGSGGSGPRGVQALLCACTSCL QANYTCETDGACMVSIFNLDGMEHHVRTCIPKVELVPAGK PFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPS MWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQ RLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLPLFVQ RTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSRE ERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWL VSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHM EIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRH DAVTDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKC ADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPSDPSI EEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYAN GAARLTALRIKKTLSQLSVQEDVKI
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab132045 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB WB: Use at an assay dependent concentration.
    SDS-PAGE SDS-PAGE: Use at an assay dependent concentration.
    ELISA ELISA: Use at an assay dependent concentration.
  • Application notesThis peptide can be used with studies using ab169981.

    • Protein info

    • Alternative names
        Activin A receptor type 1BActivin A receptor type II like kinase 4Activin A type 1B receptor
        Activin A type IB receptorActivin receptor like kinase 4Activin receptor type 1BActivin receptor type IBActivin receptor type-1BActivin receptor-like kinase 4ACTR IBACTR-IBACTRIBACV1B_HUMANACVR 1BAcvr1bACVRLK 4ACVRLK4ALK 4ALK-4ALK4Serine(threonine) protein kinase receptor R2Serine/threonine-protein kinase receptor R2SKR 2SKR2
      see all
  • FunctionOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Phosphorylates TDP2.
  • Tissue specificityExpressed in many tissues, most strongly in kidney, pancreas, brain, lung, and liver.
  • Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications    Autophosphorylated.
  • Cellular localizationMembrane.

    • Target information above from: UniProt accession P36896 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    Activin A Receptor Type IB protein (Tagged) images

    • SDS-PAGE - Activin A Receptor Type IB protein (Tagged) (ab132045)
      SDS-PAGE - Activin A Receptor Type IB protein (Tagged) (ab132045)
      12.5% SDS-PAGE analysis of ab132045 stained with Coomassie Blue.

    References for Activin A Receptor Type IB protein (Tagged) (ab132045)

    ab132045 has not yet been referenced specifically in any publications.

    Publishing research using ab132045 ? Please let us know so that we can cite the reference in this datasheet

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