You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Activin A Receptor Type IC peptide (ab74349)

Submit an Abreview Submit a Question

Overview

  • Product nameActivin A Receptor Type IC peptideSee all Activin A Receptor Type IC proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 100 - 200 of Human Activin A Receptor Type IC.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab65088 - Activin A Receptor Type IC antibody.
  • Protein length493 amino acids

    • Properties

  • Purity70 - 90% by HPLC
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

  • Application notesThis peptide can be used with studies using ab65088.

    • Protein info

    • Alternative names
        Activin A receptor, type ICActivin receptor like kinase 7Activin receptor type 1C precursor
        Activin receptor type ICActivin receptor type-1CActivin receptor-like kinase 7ACTR ICACTR-ICACTRICACV1C_HUMANAcvr1cACVRLK7ALK 7ALK-7ALK7
      see all
  • FunctionSerine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
  • Tissue specificityPresent in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy.
  • Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • Cellular localizationMembrane.

    • Target information above from: UniProt accession Q8NER5 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for Activin A Receptor Type IC peptide (ab74349)

    ab74349 has not yet been referenced specifically in any publications.

    Publishing research using ab74349 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab74349 Submit a Question for ab74349

    There are currently no Abreviews or Questions for ab74349.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"