![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Activin Receptor Type IIA antibody [MM0058-6J16] (ab78412) image](#Activin-Receptor-Type-IIA-Primary-antibodies-ab78412-1.jpg)
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Products:Signal Transduction >> Metabolism >> Amino Acids
Overview
Product name
Anti-Activin Receptor Type IIA antibody [MM0058-6J16]
See all Activin Receptor Type IIA products (7) ...
Description
Mouse monoclonal [MM0058-6J16] to Activin Receptor Type IIA
Specificity
Specific for human Activin RIIA. No cross reactivity was found to hActivin RI and RIIB.
Tested applications
WB, IHC-Pmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse
Immunogen
Recombinant Activin RIIA extra cellular domain
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Clone number
MM0058-6J16
Isotype
IgG2
Research areas
Stem Cells >> Signaling Pathways >> TGF beta >> Surface Molecules
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> Other Kinases
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin Binding Proteins
Signal Transduction >> Metabolism >> Amino Acids
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Activin Receptor Type IIA antibody [MM0058-6J16] (ab78412)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Activin Receptor Type IIA antibody [MM0058-6J16] (ab78412) image](/ps/datasheet/images/78/ab78412/Activin-Receptor-Type-IIA-Primary-antibodies-ab78412-1.jpg)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab78412 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/100 - 1/1000.Predicted molecular weight: 58 kDa.
IHC-P: 1/50 - 1/100.
Target
Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
Sequence similarities
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Contains 1 protein kinase domain.
Cellular localization
Membrane.
Target information above from: UniProt accessionP27037
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Activin A receptor type IIA antibody
- Activin receptor type 2A antibody
- Activin receptor type IIA antibody
see all
Database links
- Entrez Gene: 92 Human
- Entrez Gene: 11480 Mouse
- Omim: 102581 Human
- SwissProt: P27037 Human
- SwissProt: P27038 Mouse
- Unigene: 470174 Human
- Unigene: 314338 Mouse
Anti-Activin Receptor Type IIA antibody [MM0058-6J16] images:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Activin Receptor Type IIA antibody [MM0058-6J16] (ab78412)
ab78412 at 1/100 dilution staining Activin Receptor Type IIA in human placental tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin embedded sections).
References for Anti-Activin Receptor Type IIA antibody [MM0058-6J16] (ab78412)
ab78412 has not yet been referenced specifically in any publications.
Publishing research using ab78412? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"