Activin Receptor Type IIA peptide (ab101080)

Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab101080 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

  • ReconstitutionThe synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.

General info

  • Alternative names
    • Activin A receptor type IIA
    • Activin receptor type 2A
    • Activin receptor type IIA
    • Activin receptor type-2A
    • ACTR 2
    • ACTR IIA
    • ACTR-IIA
    • ACTR2
    • ACTRII
    • ActRIIa
    • Acvr 2
    • Acvr 2A
    • Acvr2
    • Acvr2a
    • AVR2A_HUMAN
    • OTTHUMP00000197918
    see all
  • FunctionOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
  • Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 protein kinase domain.
  • Cellular localizationMembrane.
  • Target information above from: UniProt accession P27037 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

References for Activin Receptor Type IIA peptide (ab101080)

ab101080 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"