Anti-Acyl-coenzyme A Thioesterase 4 antibody (ab121116)

Overview

• Product nameAnti-Acyl-coenzyme A Thioesterase 4 antibodySee all Acyl-coenzyme A Thioesterase 4 primary antibodies ...
• Description
  Rabbit polyclonal to Acyl-coenzyme A Thioesterase 4
• Tested applicationsIHC-P more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  antigen sequence, corresponding to C terminal amino acids 273-416 of Human Acyl-coenzyme A Thioesterase 4.

• Positive controlHuman cerebral cortex tissue; RT 4, EFO 21 and Human Liver lysates.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferpH: 7.20
  Preservative: 0.02% Sodium azide
  Constituents: 59% PBS, 40% Glycerol
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Pathways and Processes
  • Redox metabolism
  • Fatty acid oxidation

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Fatty acids

  • Signal Transduction
  • Metabolism
  • Lipid metabolism

  • Cardiovascular
  • Lipids / Lipoproteins
  • Fatty Acids
  • Synthesis

  • Cardiovascular
  • Lipids / Lipoproteins
  • Fatty Acids
  • Metabolism

  • Tags & Cell Markers
  • Subcellular Markers
  • Organelles
  • Peroxisome

Applications

Target

• FunctionAcyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs.
• Tissue specificityStrongest expression in liver and kidney and weaker expression in placenta, heart, and muscle.
• Sequence similaritiesBelongs to the C/M/P thioester hydrolase family.
• Cellular localizationPeroxisome.

Target information above from: UniProt accession Q8N9L9 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 122970 Human
  • Omim: 614314 Human
  • SwissProt: Q8N9L9 Human
  • Unigene: 49433 Human

• Alternative names
  ACOT4 antibodyACOT4_HUMAN antibodyAcyl-CoA thioesterase 4 antibody

  Acyl-coenzyme A thioesterase 4 antibodyPeroxisomal acyl CoA thioesterase 2B antibodyPeroxisomal acyl coenzyme A thioester hydrolase Ib antibodyPeroxisomal long-chain acyl-CoA thioesterase Ib antibodyPTE-2b antibodyPTE-Ib antibodyPte1b antibodyPte2b antibody

  see all

Anti-Acyl-coenzyme A Thioesterase 4 antibody images

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Acyl-coenzyme A Thioesterase 4 antibody (ab121116)
  ab121116 at 1/40 dilution staining Acyl-coenzyme A Thioesterase 4 in Paraffin-embedded Human cerebral cortex tissue by Immunohistochemistry.
• 

  Western blot - Anti-Acyl-coenzyme A Thioesterase 4 antibody (ab121116)
  All lanes : Anti-Acyl-coenzyme A Thioesterase 4 antibody (ab121116) at 1/250 dilution
  
  Lane 1 : RT 4 cell lysate
  Lane 2 : EFO 21 cell lysate
  Lane 3 : U 138 MG cell lysate
  Lane 4 : Human liver lysate
  Lane 5 : Human tonsil lysate