Anti-Acyl-coenzyme A Thioesterase 4 antibody (ab121116)

Overview

  • Product nameAnti-Acyl-coenzyme A Thioesterase 4 antibodySee all Acyl-coenzyme A Thioesterase 4 primary antibodies ...
  • Description
    Rabbit polyclonal to Acyl-coenzyme A Thioesterase 4
  • Tested applicationsWB, IHC-P more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence, corresponding to C terminal amino acids 273-416 of Human Acyl-coenzyme A Thioesterase 4.

  • Positive control
    • Human cerebral cortex tissue; RT 4, EFO 21 and Human Liver lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab121116 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB Use at an assay dependent concentration.
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionAcyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs.
  • Tissue specificityStrongest expression in liver and kidney and weaker expression in placenta, heart, and muscle.
  • Sequence similaritiesBelongs to the C/M/P thioester hydrolase family.
  • Cellular localizationPeroxisome.
  • Target information above from: UniProt accession Q8N9L9 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • Alternative names
    • ACOT4 antibody
    • ACOT4_HUMAN antibody
    • Acyl-CoA thioesterase 4 antibody
    • Acyl-coenzyme A thioesterase 4 antibody
    • Peroxisomal acyl CoA thioesterase 2B antibody
    • Peroxisomal acyl coenzyme A thioester hydrolase Ib antibody
    • Peroxisomal long-chain acyl-CoA thioesterase Ib antibody
    • PTE-2b antibody
    • PTE-Ib antibody
    • Pte1b antibody
    • Pte2b antibody
    see all

Anti-Acyl-coenzyme A Thioesterase 4 antibody images

  • ab121116 at 1/40 dilution staining Acyl-coenzyme A Thioesterase 4 in Paraffin-embedded Human cerebral cortex tissue by Immunohistochemistry.
  • All lanes : Anti-Acyl-coenzyme A Thioesterase 4 antibody (ab121116) at 1/250 dilution

    Lane 1 : RT 4 cell lysate
    Lane 2 : EFO 21 cell lysate
    Lane 3 : U 138 MG cell lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

References for Anti-Acyl-coenzyme A Thioesterase 4 antibody (ab121116)

ab121116 has not yet been referenced specifically in any publications.

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