Anti-Acyl-coenzyme A Thioesterase 8 antibody (ab70104)

Overview

  • Product nameAnti-Acyl-coenzyme A Thioesterase 8 antibodySee all Acyl-coenzyme A Thioesterase 8 primary antibodies ...
  • Description
    Mouse polyclonal to Acyl-coenzyme A Thioesterase 8
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Acyl-coenzyme A Thioesterase 8 (NP_005460.2, 1 a.a. ~ 319 a.a) full-length human protein.

  • Positive control
    • Human spleen tissue lysate and Acyl-coenzyme A Thioesterase 8 transfected 293T lysate.

Applications

Our Abpromise guarantee covers the use of ab70104 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 33 kDa (predicted molecular weight: 36 kDa).

Target

  • FunctionAcyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxisome proliferation.
  • Tissue specificityDetected in a T-cell line (at protein level). Ubiquitous.
  • Sequence similaritiesBelongs to the C/M/P thioester hydrolase family.
  • Cellular localizationPeroxisome.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACTEIII antibody
    • Acot8 antibody
    • ACOT8_HUMAN antibody
    • Acyl CoA thioesterase 8 antibody
    • Acyl-CoA thioesterase 8 antibody
    • Acyl-coenzyme A thioesterase 8 antibody
    • Choloyl coenzyme A thioesterase antibody
    • Choloyl-coenzyme A thioesterase antibody
    • hACTE III antibody
    • hACTE-III antibody
    • hACTEIII antibody
    • HIV Nef associated acyl CoA thioesterase antibody
    • HIV-Nef-associated acyl-CoA thioesterase antibody
    • HNAACTE antibody
    • hTE antibody
    • Long chain fatty acyl CoA hydrolase antibody
    • Palmitoyl CoA hydrolase antibody
    • Peroxisomal acyl CoA thioesterase 1 antibody
    • Peroxisomal acyl coenzyme A thioester hydrolase 1 antibody
    • Peroxisomal acyl-coenzyme A thioester hydrolase 1 antibody
    • Peroxisomal long chain acyl CoA thioesterase 1 antibody
    • Peroxisomal long-chain acyl-CoA thioesterase 1 antibody
    • PTE 1 antibody
    • PTE 2 antibody
    • PTE-1 antibody
    • PTE-2 antibody
    • PTE1 antibody
    • PTE2 antibody
    • Thioesterase II antibody
    see all

Anti-Acyl-coenzyme A Thioesterase 8 antibody images

  • Anti-Acyl-coenzyme A Thioesterase 8 antibody (ab70104) at 1/500 dilution + human spleen tissue lysate at 25 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 36 kDa
    Observed band size : 33 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-Acyl-coenzyme A Thioesterase 8 antibody (ab70104) at 1/500 dilution

    Lane 1 : Acyl-coenzyme A Thioesterase 8 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 36 kDa
    Observed band size : 33 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 35 kDa. We are unsure as to the identity of these extra bands.

References for Anti-Acyl-coenzyme A Thioesterase 8 antibody (ab70104)

ab70104 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"