Overview

  • Product nameAnti-Adducin antibodySee all Adducin primary antibodies ...
  • Description
    Rabbit polyclonal to Adducin
  • Specificityab58480 detects endogenous levels of total ADD1 protein.
  • Tested applicationsIHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic non-phosphopeptide derived from human ADD1 around the phosphorylation site of threonine 445 (E-K-TP-R-W).

  • Positive control
    • Huamn breast carcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab58480 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent dilution.
ELISA 1/10000.

Target

  • RelevanceAdducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
  • Cellular localizationCytoplasm › cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • Database links
  • Alternative names
    • ADD 1 antibody
    • ADD 2 antibody
    • ADD 3 antibody
    • ADD A antibody
    • ADD B antibody
    • ADD1 antibody
    • ADD2 antibody
    • ADD3 antibody
    • ADDA antibody
    • ADDB antibody
    • ADDL antibody
    • Adducin 1 (alpha) antibody
    • Adducin 1 antibody
    • Adducin 2 (beta) antibody
    • Adducin 2 antibody
    • Adducin 3 (gamma) antibody
    • Adducin 3 antibody
    • Adducin like antibody
    • Adducin like protein 70 antibody
    • Adducin1 antibody
    • Adducin2 antibody
    • Adducin3 antibody
    • Alpha adducin antibody
    • Beta adducin antibody
    • Erythrocyte adducin alpha subunit antibody
    • Erythrocyte adducin subunit alpha antibody
    • Erythrocyte adducin subunit beta antibody
    • Gamma adducin antibody
    • MGC3339 antibody
    • MGC44427 antibody
    see all

Anti-Adducin antibody images

  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab58480 at a dilution of 1/50. Right hand image: treated with immunising peptide. Left hand image: untreated.

References for Anti-Adducin antibody (ab58480)

ab58480 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"