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Anti-Adducin (phospho S662) antibody - Actin associated protein (ab14375)

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1 question for ab14375

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Question 1

Monday 25-June-2007

Does this antibody recognize just the phosphorylated form of ADD3 or can it also recognize the native, unphosphorylated form?

ANSWER:

 

Thank you for your enquiry.

This polyclonal antibody is very specific for a phosphorylated serine. It recognizes the phosphorylated serine in a number of Adducin isoforms. Recognizes the phosphorylated serine 662 of human g-Adducin, phosphorylated serine 724 of a-Adducin and phosphorylated serine 713 of b-Adducin. The surrounding aa sequence in all these cases is at least 12 of 13.

I can also confirm that the antibody does not recognize non-phosphorylated human adducin.

I hope this information will be useful to you. Should you require any further information, please do not hesitate to contact me.

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